CAS 6677-98-1

(11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl propanoate

Description:

The chemical substance known as (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl propanoate, with the CAS number 6677-98-1, is a synthetic steroid derivative. It is characterized by its structural features, which include a pregnane backbone with hydroxyl groups at the 11 and 17 positions, and a dioxo functional group at the 3 and 20 positions. The propanoate ester group at the 21 position enhances its lipophilicity, influencing its pharmacokinetic properties. This compound is often studied for its potential biological activities, particularly in the context of hormonal regulation and therapeutic applications. Its steroidal nature suggests that it may interact with steroid hormone receptors, potentially exhibiting anti-inflammatory or immunosuppressive effects. As with many steroid derivatives, its stability, solubility, and biological activity can be significantly affected by the presence of functional groups and the overall molecular conformation. Proper handling and storage conditions are essential due to its potential biological activity and the need for safety in laboratory environments.

Formula: C₂₄H₃₄O₆

InChI: InChI=1/C24H34O6/c1-4-20(28)30-13-19(27)24(29)10-8-17-16-6-5-14-11-15(25)7-9-22(14,2)21(16)18(26)12-23(17,24)3/h11,16-18,21,26,29H,4-10,12-13H2,1-3H3/t16-,17-,18-,21+,22-,23-,24-/m0/s1

Synonyms:

• (11beta)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl propionate
• Cortisol, 21-propionate
• Pregn-4-Ene-3,20-Dione, 11,17-Dihydroxy-21-(1-Oxopropoxy)-, (11Beta)-

Hydrocortisone Impurity 43

CAS: 6677-98-1

Formula: C₂₄H₃₄O₆

Molecular weight: 418.53

Ref: 4Z-H-103113

Hydrocortisone 21-Propionate

Controlled Product

CAS: 6677-98-1

Applications Hydrocortisone 21-Propionate is a metabolite of Hydrocortisone 17-Butyrate 21-Propionate (H714665); a synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agent. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.
References Mason, J. et al.: Br. J. Dermatol., 146, 351 (2002); Sears, H.W. et al.: Clin. Therap., 19, 710 (1997); Otomo, Y.Z. et al.: Nip. Yakur. Zas., 78, 647 (1981); Kitano, Y., et al.: Acta Derm-Venereol., 66, 98 (1986)

Formula: C₂₄H₃₄O₆

Color and Shape: Neat

Molecular weight: 418.52

Ref: TR-H714775

Hydrocortisone 21-propionate

Controlled Product

CAS: 6677-98-1

Hydrocortisone 21-propionate is a synthetic corticosteroid that is used to treat inflammatory diseases. It has been shown to have anti-inflammatory and anti-allergic effects by inhibiting the release of proinflammatory cytokines, such as tumor necrosis factor (TNF). Hydrocortisone 21-propionate also reduces the production of prostaglandins and leukotrienes in tissues and cells. This drug may be used for the treatment of conditions such as prostatic hypertrophy, asthma, ulcerative colitis, and arthritis. It is also used in cancer therapy as an immunosuppressant agent. Hydrocortisone 21-propionate can be found in organic solvents such as acetone or chloroform. This drug may also be used for cell therapies or bone mass maintenance therapies due to its ability to stimulate the growth of new bone tissue.

Formula: C₂₄H₃₄O₆

Purity: Min. 95%

Molecular weight: 418.5 g/mol

Ref: 3D-GAA67798

Hydrocortisone 21-Propionate

CAS: 6677-98-1

Formula: C₂₄H₃₄O₆

Molecular weight: 418.5

Ref: ST-EA-CP-H9095