CAS 6678-14-4

(11β)-11,17-Dihydroxy-21-[(1-oxooctyl)oxy]pregn-4-ene-3,20-dione

Description:

The chemical substance known as (11β)-11,17-Dihydroxy-21-[(1-oxooctyl)oxy]pregn-4-ene-3,20-dione, with the CAS number 6678-14-4, is a synthetic steroid derivative. It features a pregnane backbone, which is characteristic of many steroid hormones, and includes hydroxyl groups at the 11 and 17 positions, contributing to its biological activity. The presence of the 1-oxooctyl group indicates that it has a long hydrophobic chain, which can influence its solubility and membrane permeability. This compound is often studied for its potential pharmacological effects, particularly in the context of anti-inflammatory and immunomodulatory activities. Its structural modifications may enhance its potency and selectivity compared to natural steroids. As with many steroid derivatives, it may interact with steroid receptors, leading to various physiological effects. Safety and efficacy profiles are typically evaluated in preclinical and clinical studies to determine its therapeutic potential.

Formula: C₂₉H₄₄O₆

InChI: InChI=1S/C29H44O6/c1-4-5-6-7-8-9-25(33)35-18-24(32)29(34)15-13-22-21-11-10-19-16-20(30)12-14-27(19,2)26(21)23(31)17-28(22,29)3/h16,21-23,26,31,34H,4-15,17-18H2,1-3H3/t21-,22-,23-,26+,27-,28-,29-/m0/s1

InChI key: InChIKey=VWVPRYMOFYIOOZ-KAQKJVHQSA-N

SMILES: C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(CCCCCCC)=O)=O)O)[H]

Synonyms:

• (11Beta)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Octanoate
• (11β)-11,17-Dihydroxy-21-[(1-oxooctyl)oxy]pregn-4-ene-3,20-dione
• 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-octanoate
• Cortisol octanoate
• Cortisol, 21-octanoate
• Hydrocortisone 21-octanoate
• Hydrocortisone octanoate
• Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-[(1-oxooctyl)oxy]-, (11β)-

Hydrocortisone 21-Octanoate

Controlled Product

CAS: 6678-14-4

Formula: C₂₉H₄₄O₆

Color and Shape: Neat

Molecular weight: 488.656

Ref: TR-H714575

Hydrocortisone-d4 21-Octanoate

Controlled Product

CAS: 6678-14-4

Formula: C₂₉D₄H₄₀O₆

Color and Shape: Neat

Molecular weight: 492.681

Ref: TR-H714577

Hydrocortisone 21-Octanoate-d15

Controlled Product

CAS: 6678-14-4

Applications Hydrocortisone 21-Octanoate-d15 is the labeled analogue of Hydrocortisone-d4 21-Octanoate (H714577), a skin permeable fatty acid hydrocortisone with potential uses in the pharmaceutical industry.
References Quintana, P.G., Baldessari, A.: Steroids, 74, 1007 (2009)

Formula: C₂₉D₁₅H₂₉O₆

Color and Shape: Neat

Molecular weight: 503.748

Ref: TR-H714578