CAS 667880-38-8

5-({1-[2-(2,4-dimethylphenoxy)ethyl]-2-methyl-1H-indol-3-yl}methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Description:

The chemical substance known as 5-({1-[2-(2,4-dimethylphenoxy)ethyl]-2-methyl-1H-indol-3-yl}methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, with the CAS number 667880-38-8, is a complex organic compound characterized by its unique structural features. It contains a thioxodihydropyrimidine core, which is a bicyclic structure that includes both nitrogen and sulfur atoms, contributing to its potential biological activity. The presence of an indole moiety suggests possible interactions with biological targets, as indoles are known for their role in various pharmacological activities. Additionally, the compound features a dimethylphenoxyethyl substituent, which may enhance its lipophilicity and influence its solubility and permeability. The overall molecular structure indicates potential for diverse applications in medicinal chemistry, particularly in the development of novel therapeutic agents. Its intricate arrangement of functional groups may also suggest interesting reactivity patterns, making it a subject of interest for further research in drug discovery and development.

Formula: C₂₄H₂₃N₃O₃S

Synonyms:

• IAC-8
• 5-({1-[2-(2,4-dimethylphenoxy)ethyl]-2-methyl-1H-indol-3-yl}methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

ZLDI-8

CAS: 667880-38-8

Formula: C₂₄H₂₃N₃O₃S

Purity: 98.78%

Molecular weight: 433.5227

Ref: IN-DA01V1VX

ZLDI-8

CAS: 667880-38-8

ZLDI-8

Purity: ≥98%

Molecular weight: 433.52g/mol

Ref: 54-BUP04567

ZLDI-8

CAS: 667880-38-8

ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.

Formula: C₂₄H₂₃N₃O₃S

Purity: 98.09%

Color and Shape: Solid

Molecular weight: 433.52

Ref: TM-T13410

ZLDI-8

CAS: 667880-38-8

ZLDI-8 is a prognostic marker that can be used to predict the response of a patient with non-small-cell lung cancer to chemotherapy. The assay detects the presence of ZLDI-8 protein in cell culture, and can be used to predict the response of a patient with non-small-cell lung cancer to chemotherapy. The level of ZLDI-8 protein in cells is not affected by etoposide treatment, indicating that it is not an oncogene. ZLDI-8 expression is correlated with tumor progression and has been shown to be involved in epithelial mesenchymal transition (EMT). This protein also has potential as an antitumor agent due to its ability to inhibit tumor growth and induce apoptosis through inhibition of angiogenesis, proliferation, and invasion.

Formula: C₂₄H₂₃N₃O₃S

Purity: Min. 95%

Molecular weight: 433.5 g/mol

Ref: 3D-SBB88038