
CAS 66791-71-7
:1-epi-Calcitriol
Description:
1-epi-Calcitriol, with the CAS number 66791-71-7, is a biologically active form of vitamin D, specifically a stereoisomer of calcitriol. It plays a crucial role in calcium and phosphate metabolism, influencing bone health and mineralization. This compound is characterized by its ability to bind to the vitamin D receptor, thereby regulating gene expression related to calcium absorption in the intestines and calcium reabsorption in the kidneys. 1-epi-Calcitriol exhibits similar biological activity to calcitriol but may have distinct pharmacological properties, potentially offering advantages in therapeutic applications. It is typically synthesized through chemical modification of vitamin D precursors and is used in research to explore its effects on various physiological processes. The substance is generally stable under standard laboratory conditions but should be handled with care due to its potent biological effects. As with other vitamin D analogs, its use in clinical settings is subject to ongoing research to fully understand its efficacy and safety profiles.
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Found 6 products.
Calcitriol EP Impurity B (epi-Calcitriol)
CAS:Formula:C27H44O3Color and Shape:White To Off-White SolidMolecular weight:416.65Impurity B of Calcitriol
CAS:<p>Impurity B is a byproduct of Calcitriol, the active hormone form of vitamin D3 and VDR activator.</p>Formula:C27H44O3Purity:98%Color and Shape:SolidMolecular weight:416.641-epi-Calcitriol
CAS:Controlled Product<p>Stability Light Sensitive, Temperature sensitive<br>Applications An impurity of Calcitriol (C144500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Myrtle, J.F., et al.: J. Biol. Chem., 245, 1190 (1970), Lawson, D.E.M., et al.: Nature, 230, 228 (1971), Norman, A.W., et al.: Science, 173, 51 (1971), Suda, T., et al.: Vitamins, 45, 175 (1972), Muindi, J.R., et al.: Clin. Pharmacol. Ther., 72, 648 (2002),<br></p>Formula:C27H44O3Color and Shape:NeatMolecular weight:416.64






