CAS 667931-33-1

Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[1-ethyl-1-(4-ethylphenyl)propyl]-4,5,6,7-tetrahydro-2,7,7-trimethyl-5-phenyl-, (5R)-, 4-methylbenzenesulfonate (1:1)

Description:

Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[1-ethyl-1-(4-ethylphenyl)propyl]-4,5,6,7-tetrahydro-2,7,7-trimethyl-5-phenyl-, (5R)-, 4-methylbenzenesulfonate (1:1), identified by CAS number 667931-33-1, is a complex organic compound characterized by its unique structural features. This substance contains a pyrazolo-pyrimidine core, which is a bicyclic structure known for its biological activity, particularly in medicinal chemistry. The presence of various functional groups, including a carboxamide and a sulfonate, suggests potential solubility in polar solvents and may influence its pharmacokinetic properties. The compound's stereochemistry, indicated by the (5R) designation, implies specific spatial arrangements that can affect its interaction with biological targets. Additionally, the presence of ethyl and phenyl substituents enhances its lipophilicity, which may contribute to its efficacy in biological systems. Overall, this compound is of interest for its potential applications in drug development, particularly in areas targeting specific receptors or enzymes due to its intricate molecular architecture.

Formula: C₃₆H₄₆N₄O₄S

Synonyms:

• Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[1-ethyl-1-(4-ethylphenyl)propyl]-4,5,6,7-tetrahydro-2,7,7-trimethyl-5-phenyl-, (5R)-, 4-methylbenzenesulfonate (1:1)

TAK-075

CAS: 667931-33-1

TAK-075 is an orally active CaSR antagonist with an IC50 value of 0.94 nM. It transiently stimulates parathyroid hormone (PTH) secretion in rats and effectively prevents significant reduction in PTH secretion due to the accumulation of active metabolites, thereby maintaining a normal secretion pattern. TAK-075 is applicable in research related to metabolic diseases and osteoporosis.

Formula: C₃₆H₄₆N₄O₄S

Color and Shape: Solid

Molecular weight: 630.84

Ref: TM-T206506