CAS 66795-86-6
:α-Escin
Description:
α-Escin, also known as escin or aescin, is a triterpenoid saponin derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties. α-Escin exhibits a range of biological activities, including anti-inflammatory, antioxidant, and venotonic properties, making it useful in treating conditions related to venous insufficiency and edema. Its mechanism of action involves the stabilization of capillary walls and the reduction of vascular permeability, which helps alleviate swelling and discomfort. Additionally, α-Escin has been studied for its potential effects on microcirculation and its ability to enhance lymphatic drainage. Due to its natural origin, it is often included in herbal remedies and dietary supplements aimed at improving vascular health. However, it is important to note that while α-Escin is generally considered safe, it may cause side effects in some individuals, and its use should be approached with caution, particularly in those with allergies to horse chestnut or related plants.
Formula:C55H86O24
InChI:InChI=1/2C55H86O24/c2*1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h2*10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+;23-10-/t2*26?,27-,28-,29?,30?,31-,32-,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43+,44+,47+,48+,49-,51+,52-,53-,54-,55+/m11/s1
Synonyms:- (2S,3S,4S,5R,6R)-6-[[(3R,4S,6aR,6bS,8R,8aR,9R,10R,14bR)-9-acetoxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy]tetrahydropyran-2-carboxylic acid
- Ba 2672
- Ccris 7308
- alpha-Aescin
- alpha-Aescusan
- alpha-Escin
- alpha-Reparil
- α-Escin
- α-Aescin
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