CAS 6681-15-8

Jatrorrhizine chloride

Description:

Jatrorrhizine chloride, with the CAS number 6681-15-8, is a chemical compound that belongs to the class of isoquinoline alkaloids. It is primarily derived from various plant sources, particularly those in the Menispermaceae family. This compound is characterized by its yellowish crystalline appearance and is known for its potential pharmacological properties, including anti-inflammatory and analgesic effects. Jatrorrhizine chloride exhibits a moderate solubility in water and is more soluble in organic solvents, which is typical for many alkaloids. Its molecular structure features a quaternary ammonium group, contributing to its biological activity. Research has indicated that it may interact with various biological targets, making it of interest in medicinal chemistry. However, like many alkaloids, it may also exhibit toxicity at higher concentrations, necessitating careful handling and dosage considerations in any therapeutic applications. Overall, Jatrorrhizine chloride represents a compound of interest in both natural product chemistry and pharmacology.

Formula: C₂₀H₂₀NO₄·Cl

InChI: InChI=1S/C20H19NO4.ClH/c1-23-18-5-4-12-8-16-14-10-19(24-2)17(22)9-13(14)6-7-21(16)11-15(12)20(18)25-3;/h4-5,8-11H,6-7H2,1-3H3;1H

InChI key: InChIKey=JKMUUZMCSNHBAX-UHFFFAOYSA-N

SMILES: O(C)C=1C=C2C=3[N+](=CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1O.[Cl-]

Synonyms:

• Berbinium, 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy-, chloride
• Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, chloride
• Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-2,9,10-trimethoxy-, chloride (1:1)
• Jatrorrhizine Hcl(Rg)
• Jatrorrhizine chloride
• Jatrorrhizine hydrochloride
• NSC 645313
• Neprotine chloride

Jatrorrhizine Chloride

CAS: 6681-15-8

Formula: C₂₀H₂₀ClNO₄

Purity: >95.0%(T)(HPLC)

Color and Shape: Orange to Red powder to crystal

Molecular weight: 373.83

Ref: 3B-J0037

Jatrorrhizine chloride

CAS: 6681-15-8

Formula: C₂₀H₂₀ClNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 373.8301

Ref: IN-DA006R07

Jatrorrhizine chloride

CAS: 6681-15-8

Jatrorrhizine chloride

Purity: ≥98%

Molecular weight: 373.8g/mol

Ref: 54-BUP10323

Jatrorrhizine chloride

CAS: 6681-15-8

Formula: C₂₀H₂₀CLNO₄

Molecular weight: 373.83

Ref: 7W-GY6611

Jatrorrhizine chloride

CAS: 6681-15-8

Jatrorrhizine chloride

Purity: 98%

Molecular weight: 373.83g/mol

Ref: 54-OR1026255

Jatrorrhizine Chloride

CAS: 6681-15-8

Formula: C₂₀H₂₀NO₄·Cl

Color and Shape: Yellow Solid

Molecular weight: 338.39 35.45

Ref: 4Z-J-002001

Jatrorrhizine chloride

CAS: 6681-15-8

Jatrorrhizine hydrochloride has lipid lowering effects, it can ameliorate hyperlipidemia via the suppression of lipogenesis and the enhancement of lipid oxidation in the liver. It exhibits a potent inhibitory effect toward neuraminidase of the H7N9 (N9) avian influenza virus, it also can potentiate the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza. Jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate, can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity.

Formula: C₂₀H₂₀ClNO₄

Purity: 95%~99%

Molecular weight: 373.833

Ref: BP-BP0809

Jatrorrhizine chloride

CAS: 6681-15-8

Natural alkaloid

Formula: C₂₀H₂₀NO₄Cl

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 373.84

Ref: 5G-89530

Jatrorrhizine chloride

CAS: 6681-15-8

Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.

Formula: C₂₀H₂₀ClNO₄

Purity: 99.79%

Color and Shape: Solid

Molecular weight: 373.8

Ref: TM-T4912

Jatrorrhizine Chloride

CAS: 6681-15-8

Formula: C₂₀H₂₀NO₄·Cl

Color and Shape: Neat

Molecular weight: 373.83

Ref: TR-J210910

Jatrorrhizine chloride

CAS: 6681-15-8

Jatrorrhizine chloride is an isoquinoline alkaloid, which is extracted from various plant sources such as the roots of Berberis species. Known for its presence in traditional medicinal plants, this compound exhibits a range of biochemical activities. As an alkaloid, it plays a role in modulating biological processes through its interaction with various cellular targets.

Formula: C₂₀H₂₀ClNO₄

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 373.83 g/mol

Ref: 3D-FJ146885