CAS 66840-03-7

Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-

Description:

Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro- is a modified nucleotide that plays a significant role in biochemical processes, particularly in nucleic acid synthesis and cellular signaling. This compound features a cytidine base, a ribose sugar that has been modified to a 2'-deoxy-2'-fluoro configuration, and a triphosphate group. The presence of the fluorine atom at the 2' position enhances the stability of the molecule against enzymatic degradation, making it useful in various biochemical applications, including as a potential therapeutic agent or in the development of nucleotide analogs. The triphosphate moiety is crucial for energy transfer and is involved in the synthesis of RNA and DNA. Additionally, this compound can serve as a substrate for polymerases, facilitating the incorporation of modified nucleotides into nucleic acids. Its unique structural characteristics contribute to its functionality in molecular biology and medicinal chemistry, making it a subject of interest in research focused on nucleic acid manipulation and drug development.

Formula: C₉H₁₅FN₃O₁₃P₃

2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium

CAS: 66840-03-7

2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium is a modified nucleoside analog where the base is cytosine, the sugar is deoxyribose with a fluoro modification at the 2' position, and the molecule is phosphorylated at the 5' position with a triphosphate group.

Formula: C₉H₁₁FLi₄N₃O₁₃P₃

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 508.88 g/mol

Ref: 3D-ND09530

2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt - 100mM aqueous solution

CAS: 66840-03-7

2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is a nucleoside that is used in the synthesis of DNA. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an antiviral, antineoplastic, and anticancer agent. It has been shown to be active against some strains of HIV and herpes viruses. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt also inhibits DNA polymerase and RNA polymerase, preventing viral replication and transcription. The phosphate group on the 5' end of this molecule can be modified to produce phosphoramidites, diphosphates, or triphosphates.

Formula: C₉H₁₁FN₃O₁₃P₃·Li₄

Purity: Min. 95%

Molecular weight: 508.88 g/mol

Ref: 3D-NF46155