CAS 66852-54-8
:Halobetasol propionate
Description:
Halobetasol propionate is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties, particularly in dermatological applications. It is characterized by its high potency, making it effective in treating various skin conditions such as psoriasis and eczema. The substance is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents. Its mechanism of action involves the inhibition of inflammatory mediators, thereby reducing redness, swelling, and itching associated with skin disorders. Halobetasol propionate is typically formulated in topical preparations, including creams, ointments, and lotions, and is applied directly to the affected area. Due to its potency, it is generally recommended for short-term use and under medical supervision to minimize potential side effects, such as skin thinning or systemic absorption. As with all corticosteroids, proper usage guidelines should be followed to ensure safety and efficacy.
Formula:C25H31ClF2O5
InChI:InChI=1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1
InChI key:InChIKey=BDSYKGHYMJNPAB-LICBFIPMSA-N
SMILES:O(C(CC)=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
Synonyms:- (6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- Bmy 30056
- Cgp 14458
- Halobetasol propionate
- Miracorten
- Ulobetasol propionate
- Ultravate
- ethyl (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17-carboxylate
- (6alpha,8xi,10xi,13xi,14xi,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
- 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
- See more synonyms
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Found 15 products.
Halobetasol Propionate
CAS:Formula:C25H31ClF2O5Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:484.96Halobetasol Propionate
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C25H31ClF2O5Color and Shape:White Off-White PowderMolecular weight:484.18281Halobetasol-d3 Propionate
CAS:Formula:C25H28D3ClF2O5Color and Shape:White To Off-White SolidMolecular weight:487.98Halobetasol Propionate-d5
CAS:Formula:C25H26D5ClF2O5Color and Shape:White To Off-White SolidMolecular weight:490.00Halobetasol Propionate
CAS:Formula:C25H31ClF2O5Color and Shape:Off-White SolidMolecular weight:484.96Halobetasol Propionate
CAS:Controlled ProductFormula:C25H31ClF2O5Color and Shape:NeatMolecular weight:484.96Halobetasol propionate
CAS:Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
Formula:C25H31ClF2O5Purity:99.89%Color and Shape:Distributed As 0 05% OintmentMolecular weight:484.96Halobetasol Propionate
CAS:Controlled ProductApplications Anti-inflammatory; a dermatologic agent commonly used to treat psoriasis
References Pearce, D., et al.: Int. J. Dermatol., 45, 370 (2006),Formula:C25H31ClF2O5Color and Shape:NeatMolecular weight:484.96Halobetasol Propionate-d5
CAS:Controlled ProductFormula:C25D5H26ClF2O5Color and Shape:NeatMolecular weight:489.991Halobetasol propionate
CAS:Controlled ProductHalobetasol propionate is a corticosteroid that is used to treat inflammatory skin diseases such as psoriasis and atopic dermatitis. It belongs to the group of drugs known as topical steroids, which are applied to the skin. Halobetasol propionate may also be used to treat choroidal neovascularization (CNV) or ocular hypertension in patients with age-related macular degeneration, but it is not approved for this use. The mechanism of action of halobetasol propionate is not fully understood, but it has been shown to inhibit the activity of certain proteins involved in inflammation. Halobetasol propionate has been shown to be more effective than hydrocortisone in reducing the severity and frequency of cutaneous lesions in patients with psoriasis.Formula:C25H31ClF2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:484.96 g/molHalobetasol propionate-d3
CAS:Controlled ProductHalobetasol propionate-d3 is a biocompatible polymer that binds to the effector proteins of the inflammatory response. It is used in the treatment of inflammatory bowel disease, psoriasis, and other skin diseases. Halobetasol propionate-d3 has been shown to be effective against plaque and cutaneous lesions in patients with psoriasis. This drug also inhibits the production of proinflammatory cytokines (IL-1β, IL-6, IL-8) and chemokines (MCP-1) by monocytes. The drug has been shown to be effective against autoimmune diseases due to its ability to inhibit TNFα production from macrophages. Halobetasol propionate-d3 is compatible with blood group A, B, and AB.
Formula:C25H31ClF2O5Purity:Min. 95%Molecular weight:484.96 g/mol
