CAS 6686-70-0

destruxin A from metarhizium anisopliae

Description:

Destruxin A is a cyclic peptide toxin produced by the fungus Metarhizium anisopliae, which is known for its insecticidal properties. This compound belongs to a class of molecules known as destruxins, which are characterized by their unique cyclic structure and biological activity. Destruxin A exhibits potent insecticidal effects, primarily by disrupting cellular processes in target organisms, leading to paralysis and death. Its mechanism of action involves interference with the host's immune response and apoptosis pathways. The compound has garnered interest for its potential applications in biopesticides and as a model for developing new therapeutic agents due to its specific action on insect cells. Additionally, destruxin A has been studied for its cytotoxic effects on mammalian cells, indicating a broader spectrum of biological activity. However, its use in agriculture and medicine requires careful consideration of its toxicity and environmental impact. Overall, destruxin A represents a fascinating example of natural products with significant implications in both pest management and pharmacology.

Formula: C₂₉H₄₇N₅O₇

InChI: InChI=1/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)

SMILES: C=CCC1C(=O)N2CCCC2C(=NC(C(C)CC)C(=O)N(C)C(C(C)C)C(=O)N(C)C(C)C(=NCCC(=O)O1)O)O

Synonyms:

• Destruxin A
• Brn 0601694
• Nsc 361126
• 3-(butan-2-yl)-5,8,9-trimethyl-6-(propan-2-yl)-16-(prop-2-en-1-yl)dodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone

Destruxin A

CAS: 6686-70-0

Formula: C₂₉H₄₇N₅O₇

Purity: ≥ 97.0%

Color and Shape: White, off-white or pale yellow powder

Molecular weight: 577.71

Ref: 7W-GL2718

Destruxin A from Metarhizium anisopliae

CAS: 6686-70-0

Destruxin A from Metarhizium anisopliae

Color and Shape: Solid

Molecular weight: 577.71g/mol

Ref: 54-BID1011

Destruxin A

CAS: 6686-70-0

Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects.

Formula: C₂₉H₄₇N₅O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 577.71

Ref: TM-TP1564

Destruxin A

CAS: 6686-70-0

Destruxin A is a cyclodepsipeptide, which is a specialized secondary metabolite originating from the entomopathogenic fungus, Metarhizium anisopliae. This bioactive compound exerts its effects through a multifaceted mode of action, primarily disrupting ion channels and perturbing cellular homeostasis within insect hosts. The interference with calcium and potassium ion fluxes leads to paralysis and ultimately death of the targeted pests, making it an effective biocontrol agent. Destruxin A holds significant potential in integrated pest management programs, particularly in agriculture, where it offers a sustainable alternative to synthetic chemical pesticides. Its specificity to insect physiology ensures minimal impacts on non-target organisms, promoting ecological balance. Studies continue to explore its application spectrum and effectiveness, seeking to optimize its deployment in various pest-infested environments, including crops and stored products.

Formula: C₂₉H₄₇N₅O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 577.71 g/mol

Ref: 3D-BD162717