CAS 669073-68-1

ZK 216348

CAS: 669073-68-1

ZK 216348 is a selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. also binds to progesterone receptors and mineralocorticoid receptors.

Formula: C₂₄H₂₃F₃N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 476.45

Ref: TM-T17291

(+)-ZK 216348

CAS: 669073-68-1

(+)-ZK 216348 is a potent, selective agonist of the nuclear hormone receptor TRβ. (+)-ZK 216348 has been shown to have transrepression activity in osteoblasts and to inhibit bone resorption by interfering with the activation of osteoclasts. (+)-ZK 216348 also inhibits inflammation and has shown anti-inflammatory activity in animal models. In addition, (+)-ZK 216348 has been found to be an effective treatment for osteoporosis without having any side-effects observed in clinical trials.

Formula: C₂₄H₂₃F₃N₂O₅

Purity: Min. 95%

Molecular weight: 476.4 g/mol

Ref: 3D-UBB07368