CAS 67-20-9

Furantoin

Description:

Furantoin, also known as nitrofurantoin, is an antibiotic primarily used to treat urinary tract infections. It belongs to the nitrofuran class of compounds and exhibits broad-spectrum antibacterial activity against various Gram-positive and Gram-negative bacteria. The chemical structure of furantoin features a nitrofuran ring, which is essential for its antimicrobial properties. It works by inhibiting bacterial protein synthesis, DNA, RNA, and cell wall synthesis, ultimately leading to bacterial cell death. Furantoin is typically administered orally and is well-absorbed in the gastrointestinal tract, with its effectiveness enhanced when taken with food. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, pulmonary toxicity. Due to its specific mechanism of action and pharmacokinetics, furantoin is particularly effective for uncomplicated urinary tract infections caused by susceptible organisms. However, it is not suitable for systemic infections or those caused by certain resistant bacteria. As with any medication, it is important to use furantoin under the guidance of a healthcare professional to ensure appropriate use and minimize potential side effects.

Formula: C₈H₆N₄O₅

InChI: InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)

InChI key: InChIKey=NXFQHRVNIOXGAQ-UHFFFAOYSA-N

SMILES: N(=CC=1OC(N(=O)=O)=CC1)N2CC(=O)NC2=O

Synonyms:

• 1-(5-Nitro-2-furfurylidenamino)hydantoin
• 1-(5-Nitro-2-furfurylideneamino)hydantoin
• 1-(5-Nitrofurfurylideneamino)Hydantoin
• 1-[(5-Nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
• 1-[(5-Nitrofurfurylidene)amino]hydantoin
• 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
• 1-[[(5-Nitro-2-furyl)methylene]amino]-2,4-imidazolidinone
• 1-{[(5-Nitrofuran-2-Yl)Methylidene]Amino}Imidazolidine-2,4-Dione
• 2,4-Imidazolidinedione, 1-[[(5-nitro-2-furanyl)methylene]amino]-
• 5-Nitrofurantoin
• Berkfurin
• Chemiofuran
• Cyantin
• Cystit
• FuaMed
• Fur-ren
• Furachel
• Furadantin
• Furadantine MC
• Furadantoin
• Furadoin
• Furadoine
• Furadonin
• Furadonine
• Furadontin
• Furalan
• Furantoin
• Furantoina
• Furatoin
• Furina
• Furobactina
• Furophen T-Caps
• Hydantoin, 1-[(5-nitrofurfurylidene)amino]-
• Ituran
• Macrobid
• Macrodantin
• Macrofuran
• N-(5-Nitro-2-furfurylidene)-1-aminohydantoin
• N-(5-Nitro-2-furfurylidine)-1-aminohydantoin
• N-(5-Nitrofurfurylidene)-1-aminohydantoin
• Nifurantin
• Nitoin
• Nitrofurantoina
• Nitrofurantoine
• Novofuran
• Nsc 2107
• Nsc 44150
• Orafuran
• Parfuran
• Trantoin
• Urantoin
• Urizept
• Uro-Tablinen
• Urodin
• Urofurin
• Urolong
• Uvamin
• Welfurin

Nitrofurantoin

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 238.16

Ref: 3B-N0883

Nitrofurantoin, 98%

CAS: 67-20-9

Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the

Formula: C₈H₆N₄O₅

Purity: 98%

Color and Shape: Yellow, Powder or crystalline powder

Molecular weight: 238.16

Ref: 02-B24079

Nitrofurantoin

CAS: 67-20-9

Color and Shape: Neat

Ref: 61-FOR0506.00

Nitrofurantoin

CAS: 67-20-9

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₆N₄O₅

Color and Shape: Yellow Powder

Molecular weight: 238.16 g/mol

Ref: 45-1464001

Nitrofurantoin

CAS: 67-20-9

Nitrofurantoin, an antibiotic, targets bacteria for urinary infections by blocking DNA, RNA, and protein synthesis.

Formula: C₈H₆N₄O₅

Purity: 99.77% - 99.96%

Color and Shape: Orange-Yellow Needles From Dil Acetic Acid 1992)

Molecular weight: 238.16

Ref: TM-T1313

1-(5-Nitro-2-furfurylidenamino)hydantoin

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.1570

Ref: IN-DA00IBNX

Nitrofurantoin

CAS: 67-20-9

Nitrofurantoin

Formula: C₈H₆N₄O₅

Purity: By hplc: 99.5% by area (Typical Value in Batch COA)

Color and Shape: yellow powder

Molecular weight: 238.15704g/mol

Ref: 54-BIN0136

Nitrofurantoin

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Color and Shape: Yellow Solid

Molecular weight: 238.16

Ref: 4Z-N-341

Nitrofurantoin

CAS: 67-20-9

Nitrofurantoin

Purity: ≥98%

Molecular weight: 238.16g/mol

Ref: 54-BUP18471

Nitrofurantoin

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Purity: ≥ 98.0% (anhydrous basis)

Color and Shape: Yellow crystalline powder

Molecular weight: 238.16

Ref: 7W-GA0512

Nitrofurantoin

Controlled Product

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Color and Shape: Neat

Molecular weight: 238.16

Ref: 04-C15570900

Nitrofurantoin

Controlled Product

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Color and Shape: Neat

Molecular weight: 238.16

Ref: 86-MM0506.00

Nitrofurantoin-13C-15N3

CAS: 67-20-9

Formula: C₇₁₃CH₆N₁₅N₃O₅

Molecular weight: 242.13

Ref: 4Z-N-3412

Nitrofurantoin

Controlled Product

CAS: 67-20-9

Applications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants
References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),

Formula: C₈H₆N₄O₅

Color and Shape: Light Yellow To Yellow

Molecular weight: 238.16

Ref: TR-N493850

Nitrofurantoin

CAS: 67-20-9

Nitrofurantoin is an antimicrobial agent, which is a synthetic chemical compound with bactericidal activity. Its source is synthetic, originating from the nitrofuran class of compounds. Nitrofurantoin's mode of action involves the inhibition of essential bacterial enzymes. It is reduced by bacterial flavoproteins to active intermediates, which subsequently alter or disrupt ribosomal proteins, DNA, and other vital macromolecules within bacterial cells, thereby inhibiting key metabolic processes.

Formula: C₈H₆N₄O₅

Purity: Min. 98 Area-%

Color and Shape: Yellow Powder

Molecular weight: 238.16 g/mol

Ref: 3D-FN02704

Nitrofurantoin - Bio-X ™

CAS: 67-20-9

Nitrofurantoin is an antibiotic that binds to the bacterial ribosome and inhibits protein synthesis. It is used to treat a wide range of infections, including urinary tract infections and its common causes such as E. coli, Citrobacter and Enterococcus.

Formula: C₈H₆N₄O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 238.16 g/mol

Ref: 3D-FN182931

Nitrofurantoin extrapure, 98-102%

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Purity: 98 - 102%

Color and Shape: Lemon - yellow, Crystal / crystalline Powder, Clear

Molecular weight: 238.16

Ref: SR-84258

1-(((5-Nitrofuran-2-yl)methylene)amino)imidazolidine-2,4-dione

CAS: 67-20-9

Formula: C₈H₆N₄O₅

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 238.159

Ref: 10-F211659