CAS 67-42-5: EGTA

Description: EGTA, or ethylene glycol tetraacetic acid, is a chelating agent commonly used in biochemistry and molecular biology. It has the ability to bind divalent metal ions, such as calcium and magnesium, which makes it particularly useful in various experimental applications, including enzyme assays and protein purification. EGTA is a colorless, crystalline solid that is soluble in water, and its structure features four acetic acid groups attached to an ethylene glycol backbone, allowing it to form stable complexes with metal ions. The pH of its solutions can significantly affect its chelating ability, with optimal performance typically observed at neutral to slightly alkaline conditions. Due to its strong affinity for calcium ions, EGTA is often employed in studies involving calcium signaling and cellular processes. Additionally, it is important to handle EGTA with care, as it can interfere with certain biochemical reactions by sequestering essential metal ions. Overall, EGTA is a versatile tool in research, providing critical insights into metal ion interactions in biological systems.

Formula: C₁₄H₂₄N₂O₁₀

InChI: InChI=1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChI key: InChIKey=DEFVIWRASFVYLL-UHFFFAOYSA-N

SMILES: O=C(O)CN(CC(=O)O)CCOCCOCCN(CC(=O)O)CC(=O)O

Synonyms:

• (Aethylen-Bis-(Oxyaethylennitrilo))-Tetraessigsaeure
• 1,2-Bis(2-aminoethoxyethane)-N,N,N',N'-tetraacetic acid
• 2,2'-Ethylenedioxybis(ethylamine)-N,N,N',N'-tetraacetic acid
• 2-[2-[2-[2-[Bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid
• 3,12-Bis(Carboxylatomethyl)-6,9-Dioxa-3,12-Diazoniatetradecane-1,14-Dioate
• 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid
• 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecanedioic acid
• 3,6-Dioxaoctane-1,8-diamine-N,N,N',N'-tetraacetic acid
• 3,6-Dioxaoctane-1,8-diamine-N,N,N′,N′-tetracetic acid
• 6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-
• Acetic acid, [ethylenebis(oxyethylenenitrilo)]tetra-
• Acide Ethylenebis(Oxyethylenenitrilo)Tetraacetique
• Acido Etilenbis(Oxietilennitrilo)Tetraacetico
• Chelest GEA
• Ebonta
• Edga
• Egta
• Ethylenbis(oxyethylennitrilo)tetraessigsaure
• Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid
• Ethylene glycol bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid
• Ethylene glycol bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid
• Ethylene glycol tetraacetic acid
• Ethylene glycol, di[2-(N,N-dicarboxylmethyl)amino]ethyl ether
• Ethylene glycol-bis-(2-aminoethyl)tetraacetic acid
• Ethylenebis(Oxyethylenenitrilo)Tetra(Acetic Acid)
• Ethylenedioxybis(Ethylenenitrilo) Tetracetic Acid
• Ethylenedioxybis(ethylenenitrilo)tetraacetic acid
• Gedta
• Glycoletherdiamine-N,N,N′,N′-tetraacetic acid
• Nsc 615010
• O,O′-Bis(2-aminoethyl)ethylene glycol-N,N,N′,N′-tetraacetic acid
• [Ethylenebis(oxyethylenenitrilo)]tetraacetic acid

Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: >95.0%(T)
• Color and Shape: White to Almost white powder to crystaline
• Molecular weight: 380.35

Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid [for Biochemical Research]

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: >95.0%(T)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 380.35

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 0.5M aq. soln., pH 8.0, autoclaved

CAS: 67-42-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₁₄H₂₄N₂O₁₀
• Color and Shape: Liquid
• Molecular weight: 380.35

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 97%

CAS: 67-42-5

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, …

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: 97%
• Color and Shape: Crystals or powder or crystalline powder, White
• Molecular weight: 380.35

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 0.5M aq. soln., pH 8.0

CAS: 67-42-5

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, …

• Formula: C₁₄H₂₄N₂O₁₀
• Color and Shape: Clear colorless, Liquid
• Molecular weight: 380.35

Ethylene glycol-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 99% EGTA

CAS: 67-42-5

• Formula: (HOOCCH₂)₂N(CH₂CH₂O)₂CH₂CH₂N(CH₂COOH)₂
• Purity: 99%
• Color and Shape: white solid
• Molecular weight: 380.35

Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 380.3478

EGTA, 99%

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: ≥ 98.5% (dried basis)
• Color and Shape: White crystalline powder
• Molecular weight: 380.35

EGTA

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: (Titration) ≥ 98.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 380.35

EGTA

CAS: 67-42-5

• Purity: 99%
• Molecular weight: 380.35g/mol

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid

CAS: 67-42-5

• Purity: 97.0%
• Color and Shape: Solid, Powder
• Molecular weight: 380.3500061035156

Ethylenebis(oxyethylenenitrilo)tetraacetic acid, 98%

CAS: 67-42-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: 98%
• Color and Shape: White, Crystalline powder
• Molecular weight: 380.35

EGTA (Ethylene glycol-bis(2-Aminoethyl Ether)-N,N,N',N'-tetra-Acetic Acid)

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Molecular weight: 380.35

EGTA

CAS: 67-42-5

Ethylenebis(oxyethylenenitrilo)tetraacetate is a glycol-derived diether with hydroxyl hydrogens replaced by 2-[bis(carboxymethyl)amino]ethyl groups.

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: 97.15% - 99.49%
• Color and Shape: White Powder
• Molecular weight: 380.35

EGTA

CAS: 67-42-5

Applications EGTA is a calcium chelator. EGTA protects mature oligodendrocytes from NO generated by S-nitroso-N-acetyl-penicillamine. …

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: >90%
• Color and Shape: Neat
• Molecular weight: 380.35

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid

CAS: 67-42-5

Chelator of bivalent ions; high affinity to calcium ions

• Formula: C₁₄H₂₄N₂O₁₀
• Color and Shape: White Off-White Powder
• Molecular weight: 380.35 g/mol

Ethylene Glycol-O-O-bis-(2-Aminoethyl) N,N,N,N-Tetraacetic Acid (EGTA) extrapure, 98%

CAS: 67-42-5

• Formula: C₁₄H₂₄N₂O₁₀
• Purity: min. 98%
• Color and Shape: White, Crystalline powder
• Molecular weight: 380.4