CAS 67-73-2
:Fluocinolone 16,17-acetonide
Description:
Fluocinolone 16,17-acetonide is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological applications. It is characterized by its potent glucocorticoid activity, which helps in reducing inflammation and alleviating symptoms associated with various skin conditions, such as eczema and psoriasis. The compound has a molecular formula that reflects its steroidal structure, featuring a cyclopentanoperhydrophenanthrene core, which is typical of corticosteroids. Fluocinolone 16,17-acetonide is typically administered topically in ointment or cream formulations, allowing for localized treatment with minimal systemic absorption. Its efficacy is attributed to its ability to inhibit the release of inflammatory mediators and modulate immune responses. Additionally, the compound is known for its relatively low risk of systemic side effects when used appropriately. However, prolonged use can lead to skin atrophy and other local adverse effects. As with all corticosteroids, it is essential to follow medical guidance regarding its use to maximize therapeutic benefits while minimizing potential risks.
Formula:C24H30F2O6
InChI:InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI key:InChIKey=FEBLZLNTKCEFIT-VSXGLTOVSA-N
SMILES:C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]
Synonyms:- (4aS,4bR,5S,6aS,6bS,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (4aS,4bR,5S,6aS,6bS,9aR,12S)-4b,12-difluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
- 16α,17α-Isopropylidene-6α,9α-difluoro-1,4-pregnadiene-11β,16α,17α,21-tetrol-3,20-dione
- 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv.
- 6-alpha,9-alpha-Difluoro-16-alpha-hydroxyprednisolone 16,17-acetonide
- 6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone
- 6alpha,9alpha-Difluoro-16alpha-hydroxyprednisolone 16,17-acetonide
- 6alpha-Fluorotriamcinolone acetonide
- 6α, 9α-Difluoro-16α-hydroxypredonisolone-16, 17-acetonide
- 6α,9-Difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17 acetal with acetone
- 6α,9-Difluoro-11β,21-dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione
- 6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide
- 6α,9α-Difluoro-16α,17α-isopropylidenedioxy-Δ1-hydrocortisone
- 6α,9α-Difluoro-16α-hydroxyprednisolone 16,17-acetonide
- 6α-Fluorotriamcinolone acetonide
- Acetonida de fluocinolona
- Acetonida de fluocinolona [INN-Spanish]
- Acetonide de fluocinolone
- Acetonide de fluocinolone [INN-French]
- Acetonido De Fluocinolona
- Ccris 3250
- Coriphate
- Cortiplastol
- Derma-Smoothe/FS
- Dermalar
- Dermatin
- Dermatin (steroid)
- FS
- Flucinar
- Flucort
- Fluocet
- Fluocinolonacetonid
- Fluocinolonacetonidum
- Fluocinolone 16,17-acetonide
- Fluocinolone 16α,17α-acetonide
- Fluocinolone acetonide [DCIT]
- Fluocinolone acetonide [USAN:INN:JAN]
- Fluocinoloni acetonidum
- Fluocinoloni acetonidum [INN-Latin]
- Fluonid
- Fluotrex
- Fluovitef
- Fluovitif
- Flupollon
- Fluvean
- Fluzon
- Hsdb 3083
- Iluvien
- Jellin
- Localyn
- Localyn Syntex
- Neo-Synalar
- Nsc 92339
- Omniderm
- Percutina
- Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-
- Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
- Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
- Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone (8CI)
- Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone
- Prodermin
- Radiocin
- Retisert
- Rs 1401At
- Rs-1401 At
- Sinaflan
- Sinalar
- Synaflan
- Synalar
- Synalar-HP
- Synamol
- Synandone
- Synandrone
- Synemol
- Synotic
- Synsac
- Tefunote
- See more synonyms
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Found 19 products.
Fluocinolone Acetonide
CAS:Formula:C24H30F2O6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:452.49FLUOCINOLONE ACETONIDE CRS
CAS:<p>FLUOCINOLONE ACETONIDE CRS</p>Formula:C24H30F2O6Color and Shape:PowderMolecular weight:452.4882FLUOCINOLONE ACETONIDE FOR SYSTEM SUITABILITY CRS
CAS:<p>FLUOCINOLONE ACETONIDE FOR SYSTEM SUITABILITY CRS</p>Formula:C24H30F2O6Color and Shape:PowderMolecular weight:452.4882Fluocinolone acetonide
CAS:Fluocinolone acetonideFormula:C24H30F2O6Purity:98.0%Color and Shape:WhiteMolecular weight:452.20105Fluocinolone Acetonide
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C24H30F2O6Color and Shape:White PowderMolecular weight:452.20105(6α,11β,16α)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Formula:C24H30F2O6Purity:97%Color and Shape:SolidMolecular weight:452.4882Fluocinolone (Acetonide)
CAS:<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Formula:C24H30F2O6Purity:99.29% - 99.82%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49Fluocinolone acetonide
CAS:Formula:C24H30F2O6Purity:98.0 - 102.0 % (anhydrous basis)Color and Shape:White or almost white powderMolecular weight:452.49Fluocinolone acetonide
CAS:Controlled ProductFormula:C24H30F2O6Color and Shape:NeatMolecular weight:452.49Fluocinolone Acetonide
CAS:Controlled ProductFormula:C24H30F2O6Color and Shape:NeatMolecular weight:452.49Fluocinolone acetonide - BP
CAS:<p>Fluocinolone acetonide is a fluorinated steroid acting as an inhibitor of nitric oxide synthase, thus preventing the production of nitric oxide and its effect on the vascular smooth muscles, resulting in reduced blood flow. Fluocinolone acetonide is a corticosteroid used in medicine for its anti-inflammatory, anti-pruritic and vasoconstrictive effects. Applied topically, it is prescribed by dermatologists to treat skin eczema, allergies, and psoriasis. In mice, fluocinolone acetonide has a proven tumour growth inhibiting activity.</p>Formula:C24H30F2O6Purity:Min. 95%Molecular weight:452.49 g/molFluocinolone acetonide
CAS:<p>Corticosteroid; anti-inflammatory; treats dermatological conditions</p>Formula:C24H30F2O6Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:452.49 g/mol
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