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CAS 6700-34-1

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Dextromethorphan hydrobromide monohydrate

Description:
Dextromethorphan hydrobromide monohydrate is a synthetic compound primarily used as a cough suppressant in over-the-counter medications. It is an opioid derivative, specifically a morphinan, but it does not possess the analgesic properties typical of opioids. This substance is characterized by its white to off-white crystalline appearance and is soluble in water, which facilitates its formulation in liquid medications. The chemical formula reflects the presence of a hydrobromide salt and a monohydrate, indicating that it contains one molecule of water per molecule of the salt. Dextromethorphan acts on the central nervous system, specifically targeting the cough center in the brain to reduce the urge to cough. It is generally well-tolerated, but potential side effects may include dizziness, nausea, and drowsiness. Due to its psychoactive properties at high doses, it is sometimes misused, leading to regulatory scrutiny. Overall, dextromethorphan hydrobromide monohydrate is a widely used therapeutic agent with a well-established safety profile when used as directed.
Formula:C18H28BrNO2
InChI:InChI=1/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17-,18-;;/m1../s1
InChI key:InChIKey=STTADZBLEUMJRG-IKNOHUQMSA-N
SMILES:O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H].Br.O
Synonyms:
  • (+)-3-Methoxy-N-methylmorphinan hydrobromide monohydrate
  • (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide Hydrate
  • 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-, hydrobromide, monohydrate
  • Morphinan, 3-methoxy-17-methyl-, hydrobromide, hydrate (1:1:1), (9α,13α,14α)-
  • Morphinan, 3-methoxy-17-methyl-, hydrobromide, monohydrate, (9α,13α,14α)-
  • d-3-Methoxy-N-methylmorphinan hydrobromide monohydrate
  • DEXTROMETHORPHAN HYDROBROMIDE, PH EUR
  • Dextromethorphan hydrobromicum, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide
  • DMHM
  • Dextromethorphan monohydrate hydrobromide, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide
  • See more synonyms
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