CAS 6707-58-0

Dequalinium

Description:

Dequalinium is a quaternary ammonium compound characterized by its broad-spectrum antimicrobial properties. It is primarily used as an antiseptic and disinfectant in various medical and dental applications. The chemical structure of dequalinium includes a central nitrogen atom bonded to two long hydrocarbon chains, which contribute to its lipophilicity and ability to disrupt microbial cell membranes. This disruption leads to the leakage of cellular contents, effectively killing bacteria, fungi, and some viruses. Dequalinium is often found in formulations for throat lozenges, mouthwashes, and topical antiseptics. Its efficacy is enhanced by its ability to adhere to mucosal surfaces, providing prolonged antimicrobial action. Additionally, dequalinium exhibits low toxicity when used as directed, making it suitable for use in sensitive areas such as the oral cavity. However, like many quaternary ammonium compounds, it can cause irritation in some individuals, and its use should be monitored in sensitive populations. Overall, dequalinium is valued for its effectiveness and versatility in infection control.

Formula: C₃₀H₄₀N₄

InChI: InChI=1S/C30H38N4/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3/p+2

InChI key: InChIKey=PCSWXVJAIHCTMO-UHFFFAOYSA-P

SMILES: C(CCCCCCCCC[N+]=1C2=C(C(N)=CC1C)C=CC=C2)[N+]=3C4=C(C(N)=CC3C)C=CC=C4

Synonyms:

• Dequalinium
• 1,1′-(1,10-Decanediyl)bis[4-amino-2-methylquinolinium]
• Decamethylenebis(4-aminoquinaldinium)
• Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-
• Quinaldinium, 1,1′-decamethylenebis[4-amino-

Dequalinium Bromide

CAS: 6707-58-0

Dequalinium Bromide inhibits HIV-1 fusion by targeting Env spikes, blocking CD4-triggered conformational shifts.

Formula: C₃₀H₄₀N₄

Color and Shape: Solid

Molecular weight: 456.67

Ref: TM-T68898