CAS 67217-55-4

Mono-6-O-(p-toluenesulfonyl)-beta-cyclodextrin

Description:

Mono-6-O-(p-toluenesulfonyl)-beta-cyclodextrin is a modified form of beta-cyclodextrin, a cyclic oligosaccharide composed of seven glucose units. This compound features a p-toluenesulfonyl group attached to the 6-position of the beta-cyclodextrin, enhancing its solubility and reactivity. The introduction of the sulfonyl group increases the hydrophobic character of the molecule, allowing it to form inclusion complexes with various organic compounds, which can be beneficial in drug delivery and formulation applications. The modification also improves the stability and bioavailability of guest molecules. Mono-6-O-(p-toluenesulfonyl)-beta-cyclodextrin is typically used in pharmaceutical and analytical chemistry for its ability to encapsulate drugs, thereby improving their solubility and release profiles. Additionally, it can serve as a chiral selector in chromatography. Its unique structural characteristics and functional properties make it a valuable compound in various chemical and industrial applications.

Formula: C₄₉H₇₆O₃₇S

InChI: InChI=1/C49H76O37S/c1-13-2-4-14(5-3-13)87(70,71)72-12-21-42-28(62)35(69)49(79-21)85-41-20(11-55)77-47(33(67)26(41)60)83-39-18(9-53)75-45(31(65)24(39)58)81-37-16(7-51)73-43(29(63)22(37)56)80-36-15(6-50)74-44(30(64)23(36)57)82-38-17(8-52)76-46(32(66)25(38)59)84-40-19(10-54)78-48(86-42)34(68)27(40)61/h2-5,15-69H,6-12H2,1H3/t15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-/m1/s1

SMILES: Cc1ccc(cc1)S(=O)(=O)OC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O2)O)O

Synonyms:

• [(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-36,37,38,39,40,41,42,43,44,45,46,47,48,49-Tetradecahydroxy-10,15,20,25,30,35-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6

Mono-6-O-(p-toluenesulfonyl)-β-cyclodextrin

CAS: 67217-55-4

Formula: C₄₉H₇₆O₃₇S

Purity: 95%

Color and Shape: Solid

Molecular weight: 1289.1705

Ref: IN-DA003S5C

6-Mono-O-(p-toluenesulfonyl)-β-cyclodextrin

CAS: 67217-55-4

6-Mono-O-(p-toluenesulfonyl)-β-cyclodextrin

Purity: 98%

Ref: 54-BICY1015

Mono-6-O-(p-toluenesulfonyl)-β-cyclodextrin

CAS: 67217-55-4

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₄₉H₇₆O₃₇S

Purity: Min. 85 Area-%

Color and Shape: Powder

Molecular weight: 1,289.17 g/mol

Ref: 3D-OM11989

Mono-(6-p-toluenesulfonyl)-β-cyclodextrin

CAS: 67217-55-4

Purity: 95%

Molecular weight: 1288.38

Ref: 10-F555007