CAS 67224-41-3
:ACTH (4-11)
Description:
ACTH (4-11), also known as Adrenocorticotropic hormone fragment, is a peptide derived from the larger pro-opiomelanocortin (POMC) molecule. This specific fragment consists of the amino acid sequence corresponding to positions 4 to 11 of the full ACTH molecule, which is involved in stimulating the adrenal cortex to produce cortisol and other glucocorticoids. The CAS number 67224-41-3 identifies this particular peptide, which is characterized by its relatively small size and specific biological activity. ACTH (4-11) retains some of the biological functions of the full-length hormone, particularly in modulating stress responses and influencing metabolic processes. It is often used in research settings to study the mechanisms of adrenal function and the effects of glucocorticoids. The peptide is typically synthesized through solid-phase peptide synthesis and may be utilized in various biochemical assays and therapeutic applications. Its stability, solubility, and interaction with receptors are important characteristics that influence its functionality in biological systems.
Formula:C50H71N15O11S
InChI:InChI=1/C50H71N15O11S/c1-77-21-18-33(52)43(69)61-36(16-17-42(67)68)46(72)65-40(24-31-26-55-28-59-31)48(74)63-38(22-29-10-3-2-4-11-29)47(73)62-35(15-9-20-56-50(53)54)45(71)64-39(23-30-25-57-34-13-6-5-12-32(30)34)44(70)58-27-41(66)60-37(49(75)76)14-7-8-19-51/h2-6,10-13,25-26,28,31,33,35-40,57H,7-9,14-24,27,51-52H2,1H3,(H,58,70)(H,60,66)(H,61,69)(H,62,73)(H,63,74)(H,64,71)(H,65,72)(H,67,68)(H,75,76)(H4,53,54,56)/t31?,33-,35-,36-,37-,38-,39-,40-/m0/s1
SMILES:CSCC[C@@H](C(=N[C@@H](CCC(=O)O)C(=N[C@@H](CC1C=NC=N1)C(=N[C@@H](Cc1ccccc1)C(=N[C@@H](CCCNC(=N)N)C(=N[C@@H](Cc1c[nH]c2ccccc12)C(=NCC(=N[C@@H](CCCCN)C(=O)O)O)O)O)O)O)O)O)N
Synonyms:- H-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-OH
- L-methionyl-L-alpha-glutamyl-3-(4H-imidazol-4-yl)-L-alanyl-L-phenylalanyl-N~5~-(diaminomethylidene)-L-ornithyl-L-tryptophylglycyl-L-lysine
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Found 3 products.
N2-(N-(N-(N2-(N-(N-(N-L-Methionyl-L-α-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-L-tryptophyl)glycyl)-L-lysine
CAS:Formula:C50H71N15O11SPurity:98%Molecular weight:1090.2576ACTH (4-11)
CAS:ACTH (4-11) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response.Formula:C50H71N15O11SPurity:98%Color and Shape:SolidMolecular weight:1090.26ACTH 4-11
CAS:<p>ACTH 4-11 is a synthetic peptide with the amino acid sequence of ACTH(1-14) that inhibits the binding of ACTH to its receptor. It has been used as a research tool to study the interactions between ACTH and its receptor. Research has shown that ACTH 4-11 can activate the receptor, and it is being studied as a potential treatment for conditions such as chronic pain. The peptide is also being investigated for use in the treatment of obesity, Alzheimer's disease, Parkinson's disease, and other neurological disorders.</p>Formula:C50H71N15O11SPurity:Min. 95%Molecular weight:1,090.3 g/mol


