CAS 67227-55-8

Primidolol

Description:

Primidolol is a beta-adrenergic antagonist, commonly classified as a non-selective beta-blocker. It is primarily used in the management of hypertension and certain cardiac conditions. The chemical structure of Primidolol features a phenolic hydroxyl group and an isopropylamino side chain, which contribute to its pharmacological activity. As a beta-blocker, it works by inhibiting the action of catecholamines like adrenaline on beta-adrenergic receptors, leading to decreased heart rate and myocardial contractility. This results in lowered blood pressure and reduced cardiac workload. Primidolol may also exhibit some intrinsic sympathomimetic activity, which can influence its overall effects on the cardiovascular system. In terms of solubility, it is generally more soluble in organic solvents than in water, which can affect its formulation and delivery in pharmaceutical applications. As with other beta-blockers, potential side effects may include fatigue, dizziness, and bradycardia, necessitating careful monitoring during treatment.

Formula: C₁₇H₂₃N₃O₄

InChI: InChI=1S/C17H23N3O4/c1-12-5-3-4-6-15(12)24-11-14(21)9-18-7-8-20-10-13(2)16(22)19-17(20)23/h3-6,10,14,18,21H,7-9,11H2,1-2H3,(H,19,22,23)

InChI key: InChIKey=RETPFDTUCPKFEC-UHFFFAOYSA-N

SMILES: C(CNCC(COC1=C(C)C=CC=C1)O)N2C(=O)NC(=O)C(C)=C2

Synonyms:

• 1-(2-{[2-Hydroxy-3-(2-methylphenoxy)propyl]amino}ethyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-[2-[[2-Hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methyl-2,4-(1H,3H)-pyrimidinedione
• 2,4(1H,3H)-pyrimidinedione, 1-[2-[[2-hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methyl-
• 67227-55-8
• Uk 11443
• Primidolol

Primidolol

CAS: 67227-55-8

Primidolol is a beta adrenergic receptor antagonist and antihypertensive agent.

Formula: C₁₇H₂₃N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 333.38

Ref: TM-T28450