CAS 67287-39-2

R-(+)-skf-81297 hydrobromide

Description:

R-(+)-SKF-81297 hydrobromide is a chemical compound primarily recognized for its role as a selective dopamine D1 receptor agonist. It is often utilized in neuropharmacological research to study the dopaminergic system and its implications in various neurological disorders. The compound is characterized by its chiral nature, with the "R" designation indicating its specific stereochemistry, which is crucial for its biological activity. As a hydrobromide salt, it is typically more soluble in water, facilitating its use in laboratory settings. R-(+)-SKF-81297 has been shown to influence locomotor activity and cognitive functions in animal models, making it a valuable tool for investigating the effects of dopamine modulation. Its pharmacological profile includes potential applications in understanding conditions such as schizophrenia, Parkinson's disease, and addiction. However, like many research chemicals, it requires careful handling and thorough understanding of its effects and mechanisms of action in biological systems.

Formula: C16H17BrClNO2

InChI: InChI=1S/C16H16ClNO2.BrH/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20;/h1-5,8,13,18-20H,6-7,9H2;1H

InChI key: RMIJGBMRNYUZRG-UHFFFAOYSA-N

SMILES: C1CNCC(C2=CC(=C(C(=C21)Cl)O)O)C3=CC=CC=C3.Br

SKF 81297 hydrobromide

CAS: 67287-39-2

SKF 81297 hydrobromide

Formula: C₁₆H₁₇BrClNO₂

Purity: ≥98%

Molecular weight: 370.67

Ref: 54-BUP21007

(R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide

CAS: 67287-39-2

Formula: C₁₆H₁₇BrClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 370.6687

Ref: IN-DA00FBJC

SKF 81297C

Controlled Product

CAS: 67287-39-2

Applications SKF 81297C is a dopamine D1 agonist (1).
References (1) Bergman, J., et. al.: J. Pharmacol. Exp. Ther., 273, 40 (1995)

Formula: C₁₆H₁₇BrClNO₂

Color and Shape: Neat

Molecular weight: 370.67

Ref: TR-S550020

SKF 81297 HBr

CAS: 67287-39-2

Formula: C₁₆H₁₆ClNO₂

Molecular weight: 289.76

Ref: 4Z-S-252001

SKF 81297 hydrobromide

CAS: 67287-39-2

D1-like dopamine receptor agonist

Formula: C₁₆H₁₆ClNO₂·HBr

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 370.67 g/mol

Ref: 3D-BS162624

SKF 81297 hydrobromide

CAS: 67287-39-2

SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.

Formula: C₁₆H₁₇BrClNO₂

Purity: 99.52%

Color and Shape: Solid

Molecular weight: 370.67

Ref: TM-T23361