CAS 67287-95-0

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide (1:1)

Description:

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide (1:1), with the CAS number 67287-95-0, is a chemical compound characterized by its complex bicyclic structure, which includes a benzazepine core. This compound features multiple functional groups, including hydroxyl (-OH) groups and a chloro substituent, contributing to its potential reactivity and biological activity. The presence of a hydrobromide salt indicates that it is in a protonated form, which can enhance its solubility in polar solvents. The tetrahydro structure suggests that it is a saturated derivative, which may influence its pharmacological properties. The methyl and phenyl substituents can affect the compound's lipophilicity and interaction with biological targets. Overall, this compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. However, specific biological activities and applications would require further investigation through experimental studies.

Formula: C₁₈H₂₀ClNO₂·BrH

InChI: InChI=1S/C18H20ClNO2.BrH/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19;/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3;1H

InChI key: InChIKey=FHYWNBUFNGHNCP-UHFFFAOYSA-N

SMILES: ClC1=C2C(C(CN(C)CC2)C3=CC(C)=CC=C3)=CC(O)=C1O.Br

Synonyms:

• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide
• 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide (1:1)
• SKF 83959 hydrobromide

SKF 83959

CAS: 67287-95-0

SKF 83959 is a drug that acts as a dopamine receptor agonist. It is used in pharmacological research to study the effects of dopamine on the central nervous system. SKF 83959 has been shown to increase locomotor activity and inhibit the release of the neurotransmitter GABA in rat caudate putamen. SKF 83959 also increases adenosine 3', 5'-cyclic monophosphate levels and camp levels in tubule cells, which may be related to its effects on energy metabolism. In addition, SKF 83959 has been shown to exhibit anti-inflammatory effects by reducing the production of proinflammatory cytokines such as IL-1β and TNF-α in mouse macrophages.

Formula: C₁₈H₂₀ClNO₂·HBr

Purity: Min. 95%

Molecular weight: 317.82 g/mol

Ref: 3D-SCA28795

SKF 83959 hydrobromide

CAS: 67287-95-0

SKF 83959 hydrobromide is a Dopamine D1-like receptor partial agonist.

Formula: C₁₈H₂₁BrClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.72

Ref: TM-T23364