CAS 6729-55-1

γ-D-Glutamylglycine

Description:

γ-D-Glutamylglycine, also known by its CAS number 6729-55-1, is a dipeptide composed of the amino acids D-glutamic acid and glycine. This compound features a peptide bond between the carboxyl group of D-glutamic acid and the amino group of glycine, resulting in a structure that is characteristic of peptides. γ-D-Glutamylglycine is notable for its role in various biochemical processes, particularly in the context of neurotransmission and cellular signaling. It is soluble in water, which is typical for many peptides, and its solubility can be influenced by factors such as pH and temperature. The presence of the D-enantiomer of glutamic acid distinguishes it from its L-counterpart, potentially affecting its biological activity and interactions with receptors. This compound may also exhibit properties relevant to research in pharmacology and biochemistry, particularly in studies related to amino acid metabolism and neurobiology. Overall, γ-D-Glutamylglycine serves as an important model for understanding peptide behavior and function in biological systems.

Formula: C₇H₁₂N₂O₅

InChI: InChI=1S/C7H12N2O5/c8-4(7(13)14)1-2-5(10)9-3-6(11)12/h4H,1-3,8H2,(H,9,10)(H,11,12)(H,13,14)/t4-/m1/s1

InChI key: InChIKey=ACIJGUBIMXQCMF-SCSAIBSYSA-N

SMILES: C(C(NCC(O)=O)=O)C[C@H](C(O)=O)N

Synonyms:

• (2R)-2-Amino-5-(carboxymethylamino)-5-oxopentanoic acid
• (2R)-2-ammonio-5-[(carboxylatomethyl)amino]-5-oxopentanoate
• <span class="text-smallcaps">D</span>-γ-Glutamylglycine
• Glutamine, N-(carboxymethyl)-, <span class="text-smallcaps">D</span>-
• Glycine, <span class="text-smallcaps">D</span>-γ-glutamyl-
• Glycine, N-<span class="text-smallcaps">D</span>-γ-glutamyl-
• Glycine, N-D-gamma-glutamyl-
• H-D-Glu(Gly-Oh)-Oh
• L-gamma-glutamylglycine
• gamma-D-Glutamylglycine
• γ-<span class="text-smallcaps">D</span>-Glutamylglycine
• D-γ-Glutamylglycine
• Glutamine, N-(carboxymethyl)-, D-
• γ-D-Glutamylglycine
• Glycine, N-D-γ-glutamyl-

H-D-Glu(Gly-OH)-OH

CAS: 6729-55-1

Formula: C₇H₁₂N₂O₅

Purity: 99%

Molecular weight: 204.1806

Ref: IN-DA00FAL6

γ-DGG

CAS: 6729-55-1

gamma-DGG is a competitive blocker of AMPA receptor.

Formula: C₇H₁₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 204.18

Ref: TM-T15369

H-D-Glu(Gly-OH)-OH

CAS: 6729-55-1

H-D-Glu(Gly-OH)-OH is a peptide that is used to study the mechanism of glutamate receptors. It has been shown to have an excitatory effect on mouse hippocampal and cerebellar purkinje neurons, with affinity values for membrane channels. It also has been shown to reduce gamma-aminobutyric acid (GABA) levels in the hippocampus and striatum, which may be due to its ability to inhibit glutamic acid decarboxylase. H-D-Glu(Gly-OH)-OH is a potent antagonist of glutamate, binding competitively at the glutamate site on ionotropic receptors. It also inhibits acidic pH and calcium ion concentrations, which are necessary for ionotropic receptor activation.

Formula: C₇H₁₂N₂O₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 204.18 g/mol

Ref: 3D-FG108033

γ-D-Glutamylglycine

Controlled Product

CAS: 6729-55-1

Formula: C₇H₁₂N₂O₅

Color and Shape: Neat

Molecular weight: 204.18

Ref: TR-G597275