CAS 672926-33-9

(αS)-1,4-Dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide

Description:

The chemical substance known as (αS)-1,4-Dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide, with the CAS number 672926-33-9, is a synthetic compound that belongs to the class of quinazoline derivatives. It features a complex molecular structure characterized by multiple functional groups, including dioxo, thiazole, and oxadiazole moieties, which contribute to its potential biological activity. The presence of these groups suggests that the compound may exhibit diverse pharmacological properties, possibly including anti-inflammatory or anticancer activities. Its stereochemistry, indicated by the (αS) designation, implies specific spatial arrangements that can influence its interaction with biological targets. The compound's solubility, stability, and reactivity are influenced by its intricate structure, making it a subject of interest in medicinal chemistry and drug development. Further studies would be necessary to elucidate its mechanism of action and therapeutic potential.

Formula: C₂₀H₂₀N₆O₄S

InChI: InChI=1S/C20H20N6O4S/c1-9(2)14(26-18(28)12-7-5-6-8-13(12)22-20(26)29)16(27)23-19-21-10(3)15(31-19)17-25-24-11(4)30-17/h5-9,14H,1-4H3,(H,22,29)(H,21,23,27)/t14-/m0/s1

InChI key: InChIKey=OHVKUJISCPKSER-AWEZNQCLSA-N

SMILES: [C@@H](C(NC=1SC(=C(C)N1)C2=NN=C(C)O2)=O)([C@H](C)C)N3C(=O)C=4C(NC3=O)=CC=CC4

Synonyms:

• (2S)-2-(2,4-Dioxo-1H-quinazolin-3-yl)-3-methyl-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-1,3-thiazol-2-yl]butanamide
• (αS)-1,4-Dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide
• 3(2H)-Quinazolineacetamide, 1,4-dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-, (αS)-

Kif15-IN-2

CAS: 672926-33-9

Kif15-IN-2

Purity: ≥98%

Molecular weight: 440.48g/mol

Ref: 54-BUP22017

Kif15-IN-2

CAS: 672926-33-9

Kif15-IN-2 is a chemical inhibitor that specifically targets the kinesin-12 family protein Kif15. It is derived from small molecule libraries through structure-based design and medicinal chemistry processes. The mode of action of Kif15-IN-2 involves the disruption of Kif15's motor function, which is crucial for the proper formation and function of the mitotic spindle during cell division. This inhibition disrupts microtubule dynamics, thereby affecting cell proliferation.

Formula: C₂₀H₂₀N₆O₄S

Purity: Min. 95%

Molecular weight: 440.48 g/mol

Ref: 3D-XBB92633

Kif15-IN-2

CAS: 672926-33-9

Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.

Formula: C₂₀H₂₀N₆O₄S

Purity: 98.17%

Color and Shape: Solid

Molecular weight: 440.48

Ref: TM-T11759