CAS 67336-99-6

Z-glycyl-L-proline-2-naphthylamide

Description:

Z-glycyl-L-proline-2-naphthylamide, with the CAS number 67336-99-6, is a synthetic compound that belongs to the class of peptide derivatives. It features a Z (benzyloxycarbonyl) protecting group on the amino group of glycine, which enhances its stability and solubility. The presence of L-proline contributes to its unique conformational properties, while the 2-naphthylamide moiety provides aromatic characteristics that can influence its biological activity and interactions. This compound is often utilized in biochemical research, particularly in studies related to peptide synthesis and enzyme inhibition. Its structural features may allow it to participate in various biochemical pathways, making it a valuable tool in medicinal chemistry and drug design. Additionally, the compound's solubility and stability can be affected by factors such as pH and temperature, which are important considerations in experimental applications. Overall, Z-glycyl-L-proline-2-naphthylamide serves as an important model for understanding peptide interactions and developing therapeutic agents.

Formula: C₂₅H₂₅N₃O₄

Synonyms:

• Z-Gly-Pro-.beta.NA
• Z-Gly-Pro-2-naphthylamide

Z-Gly-Pro-bNA

CAS: 67336-99-6

Z-Gly-Pro-bNA is a peptide that has been synthesized using recombinant DNA technology. It is a carboxyl peptidase inhibitor, which inhibits the enzyme aspartic proteases and metalloendopeptidases. Z-Gly-Pro-bNA has a specific substrate, namely tetrathionate, and it is efficient in hydrolyzing carboxyl groups. This inhibition of the catalytic activity of these enzymes leads to an increase in proline and calcitonin levels. The optimum pH for this reaction is 8.5 to 9.5 and the optimum concentration is 50 to 300 μM.

Formula: C₂₅H₂₅N₃O₄

Purity: Min. 95%

Molecular weight: 431.48 g/mol

Ref: 3D-FG110655