CAS 6735-59-7

Pralidoxime

Description:

Pralidoxime, also known by its chemical name 2-Pyridinealdoxime methyl chloride, is a chemical compound primarily used as an antidote for organophosphate poisoning, particularly in cases of nerve agent exposure. It functions by reactivating acetylcholinesterase, an enzyme inhibited by organophosphates, thereby restoring normal neurotransmission. Pralidoxime is a white to off-white crystalline solid that is soluble in water and exhibits a pH range that is typically neutral to slightly alkaline. Its molecular formula is C7H9ClN2O, and it has a molecular weight of approximately 158.61 g/mol. The compound is often administered via intravenous or intramuscular routes and is most effective when given soon after exposure to organophosphates. Pralidoxime is generally well-tolerated, but it can cause side effects such as dizziness, headache, and gastrointestinal disturbances. Due to its pharmacological properties, it is a critical component in the management of poisoning cases and is included in various medical guidelines for emergency treatment.

Formula: C₇H₉N₂O

InChI: InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1

InChI key: InChIKey=JBKPUQTUERUYQE-UHFFFAOYSA-O

SMILES: C(=NO)C=1[N+](C)=CC=CC1

Synonyms:

• Pyridinium, 2-formyl-1-methyl-, oxime
• 2-[(Hydroxyimino)methyl]-1-methylpyridinium
• 1-Methyl-2-aldoximinopyridinium
• Pralidoxime
• Pyridinium, 2-[(hydroxyimino)methyl]-1-methyl-

Pralidoxime

CAS: 6735-59-7

Pralidoxime reactivates AChE blocked by nerve agents, aiding as an organophosphate poisoning antidote.

Formula: C₇H₉N₂O

Color and Shape: Solid

Molecular weight: 137.16

Ref: TM-T73060