CAS 67443-38-3

5-Bromo-2-chloro-3-nitropyridine

Description:

5-Bromo-2-chloro-3-nitropyridine is a heterocyclic organic compound characterized by its pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. This compound features three distinct substituents: a bromine atom at the 5-position, a chlorine atom at the 2-position, and a nitro group (-NO2) at the 3-position of the pyridine ring. These substituents contribute to its chemical reactivity and potential applications in various fields, including pharmaceuticals and agrochemicals. The presence of halogens and a nitro group can enhance the compound's electrophilic properties, making it useful in further chemical transformations. Additionally, the compound's structure may influence its solubility, stability, and interaction with biological systems. As with many nitro-substituted compounds, it may exhibit specific biological activities, which could be of interest in medicinal chemistry. Safety and handling precautions should be observed due to the potential toxicity associated with halogenated and nitro compounds.

Formula: C₅H₂BrClN₂O₂

InChI: InChI=1/C5H2BrClN2O2/c6-3-1-4(9(10)11)5(7)8-2-3/h1-2H

SMILES: c1c(cnc(c1N(=O)=O)Cl)Br

Synonyms:

• 2-Pyridinecarboxylic Acid, 5-Bromo-
• 5-Bromo-2-Carboxypyridine
• 5-Bromo-2-Picolinic Acid
• Iflab-Bb F1957-0001
• Rarechem Al Bo 2390

5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

Formula: C₅H₂BrClN₂O₂

Purity: >98.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 237.44

Ref: 3B-B3963

5-Bromo-2-chloro-3-nitropyridine, 98%

CAS: 67443-38-3

5-Bromo-2-chloro-3-nitropyridine is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU

Formula: C₅H₂BrClN₂O₂

Purity: 98%

Molecular weight: 237.44

Ref: 02-H64897

5-bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

Formula: C₅H₂BrClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.4386

Ref: IN-DA00347F

5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

5-Bromo-2-chloro-3-nitropyridine

Formula: C₅H₂BrClN₂O₂

Purity: 97%

Color and Shape: Powder

Molecular weight: 237.44g/mol

Ref: 54-OR3580

5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

Formula: C₅H₂BrClN₂O₂

Purity: 97%

Color and Shape: Crystalline Powder

Molecular weight: 237.44

Ref: 10-F040847

5-Bromo-2-chloro-3-nitropyridine

Controlled Product

CAS: 67443-38-3

Applications 5-Bromo-2-chloro-3-nitropyridine (cas# 67443-38-3) is a compound useful in organic synthesis.

Formula: C₅H₂BrClN₂O₂

Color and Shape: Neat

Molecular weight: 237.44

Ref: TR-B682370

5-Bromo-2-chloro-3-nitropyridine

CAS: 67443-38-3

5-Bromo-2-chloro-3-nitropyridine is a chemical compound that has been shown to have anticancer activity. It has been found to inhibit the phosphoinositide 3 kinase (PI3K) and the mammalian target of rapamycin complex 1 (mTORC1). This drug is also a potent inhibitor of the kinase shp2, which regulates cell proliferation and apoptosis. 5-Bromo-2-chloro-3-nitropyridine inhibits tumor growth in vitro and in vivo. The mechanism of this inhibition may be due to 5-bromo-2,3 nitropyridine's ability to inhibit inflammatory genes such as NFκβ, IL1β, and IL6. 5 – Bromo - 2 - chloro - 3 - nitropyridine has also been shown to inhibit death pathways in cells by inhibiting proapoptotic protein Bax.

Formula: C₅H₂BrClN₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 237.44 g/mol

Ref: 3D-FB10581