CAS 67469-78-7

Vanoxerine dihydrochloride

Description:

Vanoxerine dihydrochloride, with the CAS number 67469-78-7, is a chemical compound that belongs to the class of phenylpiperazine derivatives. It is primarily recognized for its potential pharmacological applications, particularly in the context of neuropharmacology. The compound exhibits properties that may influence neurotransmitter systems, particularly those involving serotonin and dopamine, which are crucial for mood regulation and cognitive functions. Vanoxerine dihydrochloride is typically characterized by its dihydrochloride salt form, enhancing its solubility in aqueous solutions, which is beneficial for biological studies and potential therapeutic uses. The compound's molecular structure includes a piperazine ring, contributing to its biological activity. As with many chemical substances, safety and handling precautions are essential, as it may exhibit varying degrees of toxicity or side effects depending on dosage and exposure. Research continues to explore its full range of effects and potential applications in medicine, particularly in treating neurological disorders.

Formula: C₂₈H₃₂F₂N₂O·2ClH

InChI: InChI=1S/C28H32F2N2O.2ClH/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23;;/h1-3,5-6,8-15,28H,4,7,16-22H2;2*1H

InChI key: InChIKey=MIBSKSYCRFWIRU-UHFFFAOYSA-N

SMILES: C(OCCN1CCN(CCCC2=CC=CC=C2)CC1)(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4.Cl

Synonyms:

• 1-(2 (Bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine di-hcl
• 1-{2-[Bis(4-Fluorophenyl)Methoxy]Ethyl}-4-(3-Phenylpropyl)Piperazine Dihydrochloride
• Gbr 12909
• Gbr-12909 Dihydrochloride
• I 893
• Piperazine, 1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)-, dihydrochloride
• Piperazine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2)
• Vanoxerine hydrochloride
• Vanoxerine dihydrochloride

GBR 12909 dihydrochloride

CAS: 67469-78-7

Dopamine uptake inhibitor

Formula: C₂₈H₃₄Cl₂F₂N₂O

Molecular weight: 523.49

Ref: 02-J60684

Vanoxerine dihydrochloride(GBR12909)

CAS: 67469-78-7

Formula: C₂₈H₃₄Cl₂F₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 523.4852

Ref: IN-DA006GUR

Vanoxerine Dihydrochloride

CAS: 67469-78-7

Vanoxerine Dihydrochloride

Purity: 98%

Molecular weight: 523.49g/mol

Ref: 54-PC109171

Vanoxerine dihydrochloride

CAS: 67469-78-7

Vanoxerine dihydrochloride

Purity: ≥98%

Molecular weight: 523.49g/mol

Ref: 54-BUP06900

GBR 12909 dihydrochloride

CAS: 67469-78-7

Formula: C₂₈H₃₂F₂N₂O₂HCl

Molecular weight: 523.49

Ref: 7W-GL4399

GBR 12909 Dihydrochloride

CAS: 67469-78-7

Formula: C₂₈H₃₂F₂N₂O·2HCl

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 523.49

Ref: 3B-G0541

Vanoxerine dihydrochloride

CAS: 67469-78-7

Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)

Formula: C₂₈H₃₄Cl₂F₂N₂O

Purity: 98.16% - 98.35%

Color and Shape: White Solid

Molecular weight: 523.49

Ref: TM-T7153

GBR 12909 dihydrochloride

CAS: 67469-78-7

Dopamine reuptake inhibitor; ligand of sigma receptors

Formula: C₂₈H₃₄Cl₂F₂N₂O

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 523.49 g/mol

Ref: 3D-FG65030

GBR-12909 Dihydrochloride

CAS: 67469-78-7

Applications GBR-12909 is a potent dopamine transport blocker studied extensively in rats; it has also been classified as being able to release norepinephrine more potently than it releaes dopamine and seratonin in biological studies.
References Rothman, R.B.; et al.: Synapse, 39, 32 (2001)

Formula: C₂₈H₃₂F₂N₂O·2(HCl)

Color and Shape: Off White Solid

Molecular weight: 523.48

Ref: TR-G268005