CAS 675-20-7

2-Piperidone

Description:

2-Piperidone, with the CAS number 675-20-7, is a cyclic amide and a derivative of piperidine. It is characterized by a six-membered ring containing a nitrogen atom and a carbonyl group, making it a lactam. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and temperature. It has a distinctive odor and is soluble in water and organic solvents, which enhances its utility in various chemical reactions. 2-Piperidone is known for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the production of piperidine derivatives. It exhibits moderate toxicity and should be handled with care, following appropriate safety protocols. The compound can participate in various chemical reactions, including nucleophilic additions and cyclization processes, making it a valuable building block in organic synthesis. Its structural features contribute to its reactivity and potential applications in medicinal chemistry and material science.

Formula: C₅H₉NO

InChI: InChI=1S/C5H9NO/c7-5-3-1-2-4-6-5/h1-4H2,(H,6,7)

InChI key: InChIKey=XUWHAWMETYGRKB-UHFFFAOYSA-N

SMILES: O=C1CCCCN1

Synonyms:

• 2-Oxopiperidine
• 2-Piperidinone
• 2-Piperidon
• 2-Piperidona
• 5-Aminopentanoic acid lactam
• 5-Pentanolactam
• Delta-valerolactam
• Nsc 18894
• Nsc 2305
• Pentanoic acid, 5-amino-, lactam
• Piperidin-2-One
• Valerolactim
• α-Piperidone
• δ-Valerolactam

2-Piperidone

CAS: 675-20-7

Formula: C₅H₉NO

Purity: >98.0%(GC)

Color and Shape: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Molecular weight: 99.13

Ref: 3B-P0455

δ-Valerolactam, 98%

CAS: 675-20-7

delta-Valerolactam is the starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition. It is used as an intermediate in the preparation of other chemicals. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. So

Formula: C₅H₉NO

Purity: 98%

Color and Shape: White to yellow or brown, Crystalline or fused solid

Molecular weight: 99.13

Ref: 02-A12271

2-Piperidone

CAS: 675-20-7

Formula: C₅H₉NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 99.1311

Ref: IN-DA0033FL

δ-Valerolactam

CAS: 675-20-7

Formula: C₅H₉NO

Purity: ≥ 99.0%

Color and Shape: Light-yellow to orange crystals or solid

Molecular weight: 99.13

Ref: 7W-GK8358

Piperidin-2-one

CAS: 675-20-7

Piperidin-2-one is a piperidine derivative widely used in biochemical experiments and drug synthesis research.

Formula: C₅H₉NO

Purity: 98.46%

Color and Shape: Solid

Molecular weight: 99.13

Ref: TM-TN9362

Piperidin-2-one

CAS: 675-20-7

Piperidin-2-one

Formula: C₅H₉NO

Purity: 95%

Color and Shape: colourless/white fused solid

Molecular weight: 99.13g/mol

Ref: 54-OR5194

TerpiMix 3 2500 µg/mL in Isopropanol

Controlled Product

CAS: 105-87-3, 106-24-1, 111-02-4, 1139-30-6, 13466-78-9, 138-86-3, 4602-84-0, 4630-07-3, 4674-50-4, 489-86-1, 515-69-5, 638-36-8, 675-20-7, 6753-98-6, 7212-44-4, 7541-49-3, 77-53-2, 7787-20-4, 87-44-5

Color and Shape: Mixture

Ref: 04-A50000654IP

Smart Solutions™ TerpiMix Kit 2500 μg/mL in Isopropanol

Controlled Product

CAS: 10458-14-7, 105-87-3, 106-22-9, 106-24-1, 106-25-2, 111-02-4, 112-14-1, 1139-30-6, 116-26-7, 1196-01-6, 123-35-3, 124-76-5, 125-12-2, 127-91-3, 13466-78-9, 138-86-3, 13877-91-3, 2217-02-9, 2244-16-8, 22567-21-1, 3387-41-5, 4602-84-0, 4630-07-3, 464-43-7, 464-45-9, 4674-50-4, 469-61-4, 4695-62-9, 470-82-6, 489-86-1, 498-15-7, 499-75-2, 502-61-4, 515-69-5, 527-84-4, 535-77-3, 5392-40-5, 546-79-2, 546-80-5, 562-74-3, 586-62-9, 638-36-8, 675-20-7, 6753-98-6, 7212-44-4, 7541-49-3, 76-22-2, 77-53-2, 7787-20-4, 78-70-6, 79-92-5, 80-56-8, 87-44-5, 89-78-1, 89-79-2, 89-81-6, 89-82-7, 89-83-8, 98-55-5, 99-83-2, 99-85-4, 99-86-5, 99-87-6

Color and Shape: Kit

Ref: 04-K50000655IP

δ-Valerolactam

CAS: 675-20-7

Formula: C₅H₉NO

Purity: 98%

Color and Shape: Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 99.133

Ref: 10-F043484

δ-Valerolactam

CAS: 675-20-7

Color and Shape: Neat

Ref: 86-MM3754.03

δ-Valerolactam-d4

Controlled Product

CAS: 675-20-7

Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.
References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);

Formula: C₅H₅D₄NO

Color and Shape: Neat

Molecular weight: 103.16

Ref: TR-V091441

2-Piperidone

CAS: 675-20-7

2-Piperidone is a chemical compound that can be used to treat inflammatory bowel disease and bowel disease. It is an inhibitor of the enzyme carbonyl oxygens, which has been shown to inhibit chronic pulmonary inflammation. 2-Piperidone has also been found to have receptor activity against infectious diseases, but the mechanism is not fully understood. The reaction mechanism of 2-Piperidone is not yet known, but it has been shown in studies to inhibit the production of pro-inflammatory cytokines, such as IL-6 and TNFα, in autoimmune diseases and brain infarction. 2-Piperidone has a hydroxyl group that makes it water soluble at pH 7.4, which allows for absorption through the intestines and lungs. The pharmacokinetic properties of 2-piperidone are well studied, including its structural analysis using nuclear magnetic resonance (NMR) spectroscopy.

Formula: C₅H₉NO

Purity: Min. 95%

Color and Shape: Clear Liquid Solidified Mass

Molecular weight: 99.13 g/mol

Ref: 3D-FP09656

δ-Valerolactam

Controlled Product

CAS: 675-20-7

Applications δ-Valerolactam is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.
References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);

Formula: C₅H₉NO

Color and Shape: Neat

Molecular weight: 99.131

Ref: TR-V091440