CAS 675126-09-7

1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, hydrochloride (1:1), (1R,4R)-

Description:

1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, hydrochloride (1:1), (1R,4R)- is a chemical compound characterized by its complex structure, which includes a naphthalene ring and a tetrahydro derivative with a dichlorophenyl substituent. This compound is typically a white to off-white solid and is soluble in polar solvents, such as water and alcohols, due to the presence of the hydrochloride group. It exhibits basic properties due to the amine functional group, which can participate in hydrogen bonding. The specific stereochemistry indicated by (1R,4R) suggests that it has defined spatial arrangements that may influence its biological activity and interactions. This compound may be of interest in pharmaceutical research, particularly in the development of drugs targeting specific biological pathways. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₆H₁₅Cl₂N·ClH

InChI: InChI=1S/C16H15Cl2N.ClH/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13;/h1-5,7,9,11,16H,6,8,19H2;1H/t11-,16-;/m1./s1

InChI key: InChIKey=YKXHIERZIRLOLD-INXKOZGQSA-N

SMILES: N[C@H]1C=2C([C@H](CC1)C3=CC(Cl)=C(Cl)C=C3)=CC=CC2.Cl

Synonyms:

• 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, hydrochloride, (1R,4R)-
• (1R,4R)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
• 1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, hydrochloride (1:1), (1R,4R)-

(1R,4R)-N-desmethyl Sertraline Hydrochloride

CAS: 675126-09-7

Formula: C₁₆H₁₅Cl₂N·HCl

Molecular weight: 292.20 36.46

Ref: 4Z-S-0359

(1R,4R)-N-Desmethyl Sertraline Hydrochloride

Controlled Product

CAS: 675126-09-7

Applications A metabolite of Sertraline. N-Desmethyl sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.
References Welch, W.M., et al.: J. Med. Chem. 27, 1508-1515 (1984)

Formula: C₁₆H₁₅Cl₂N·ClH

Color and Shape: Neat

Molecular weight: 328.66

Ref: TR-D292106

(1R,4R)-N-desmethyl Sertraline hydrochloride

CAS: 675126-09-7

"(1R,4R)-N-desmethyl Sertraline, a metabolite of the selective serotonin reuptake inhibitor (SSRI) sertraline, plays a key role in its pharmacological effects."

Formula: C₁₆H₁₅Cl₂NHCl

Color and Shape: Solid

Molecular weight: 328.66

Ref: TM-T84956