CAS 67525-66-0

Clofarabine intermediate (I)

Description:

Clofarabine intermediate (I), with the CAS number 67525-66-0, is a chemical compound that serves as a precursor in the synthesis of clofarabine, an antineoplastic agent used primarily in the treatment of certain types of leukemia. This intermediate is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its reactivity and biological activity. Typically, it exhibits properties common to nucleoside analogs, such as the ability to interfere with DNA synthesis and repair mechanisms. The compound is generally soluble in polar organic solvents, which facilitates its use in various chemical reactions. Safety data indicates that, like many intermediates in pharmaceutical synthesis, it should be handled with care, as it may pose health risks if inhaled or ingested. Its stability and reactivity can be influenced by environmental conditions, making proper storage and handling essential in laboratory and industrial settings. Overall, Clofarabine intermediate (I) plays a crucial role in the pharmaceutical development of cancer therapies.

Formula: C₂₆H₂₂O₈

InChI: InChI=1/C26H22O8/c27-23(17-10-4-1-5-11-17)31-16-20-21(33-24(28)18-12-6-2-7-13-18)22(26(30)32-20)34-25(29)19-14-8-3-9-15-19/h1-15,20-22,26,30H,16H2

InChI key: InChIKey=VJYJDSXEIXFNRI-PIXQIBFHSA-N

SMILES: O(C(=O)C1=CC=CC=C1)[C@H]2[C@@H](OC(=O)C3=CC=CC=C3)[C@H](O)O[C@@H]2COC(=O)C4=CC=CC=C4

Synonyms:

• 2,3,5-Tri-O-benzoyl-beta-D-ribose
• 2,3,5-tri-O-benzoylpentofuranose
• NSC 18736
• beta-D-Ribofuranose 2,3,5-tribenzoate
• β-<span class="text-smallcaps">D</span>-Ribofuranose, 2,3,5-tribenzoate
• β-D-Ribofuranose, 2,3,5-tribenzoate
• 2,3,5-tribenzoate-β-D-Ribofuranose
• 2,3,5-TRI-O-BENZOYL-SS-D-RIBOFURANOSE
• SS-D-RIBOFURANOSE, 2,3,5-TRIBENZOATE
• (2R,3R,4R,5R)-2-((Benzoyloxy)methyl)-5-hydroxytetrahydrofuran-3,4-diyl dibenzoate
• 2,3,5-Tri-O-benzoyl-b-D-ribofuranose
• [4-(Benzoyloxy)-2-(benzoyloxymethyl)-5-hydroxyoxolan-3-yl] benzoate
• 2,3,5-TRI-O-BENZOYL-BETA-D-RIBOFURANOSE
• Clofarabine intermediate (I)

2,3,5-Tri-O-benzoyl-b-D-ribofuranose

CAS: 67525-66-0

2,3,5-Tri-O-benzoyl-b-D-ribofuranose is a custom synthesis of an oligosaccharide. It has been modified with fluorination and methylation. This is a synthetic carbohydrate that belongs to the class of saccharides. It has been synthesized from a monosaccharide and has glycosylation. The chemical formula for 2,3,5-Tri-O-benzoyl-b-D-ribofuranose is C10H14O7.

Formula: C₂₆H₂₂O₈

Purity: Min. 95%

Molecular weight: 462.45 g/mol

Ref: 3D-MT63375