CAS: 67526-95-8 - (-)-Thapsigargin

Formula: C₃₄H₅₀O₁₂

InChI: InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1

InChI key: InChIKey=IXFPJGBNCFXKPI-FSIHEZPISA-N

SMILES: O=C(OC1C(=C2C3OC(=O)C(O)(C)C3(O)C(OC(=O)CCC)CC(OC(=O)C)(C)C2C1OC(=O)CCCCCCC)C)C(=CC)C

Synonyms:

• (-)-Thapsigargin
• (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-Acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methyl-2-butenoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate
• (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-Acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate
• Azuleno[4,5-b]furan, octanoic acid deriv.
• Octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester
• Octanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester
• Octanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester, [3S-[3α,3aβ,4α,6β,6aβ,7β,8α(Z),9bα]]-

Thapsigargin, 95%

CAS: 67526-95-8

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. …

• Formula: C₃₄H₅₀O₁₂
• Purity: 95%
• Color and Shape: Wax/film, lyophilized
• Molecular weight: 650.76

Thapsigargin, 97%

CAS: 67526-95-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₃₄H₅₀O₁₂
• Purity: 97%
• Color and Shape: Colorless to white to light yellow, Powder or film
• Molecular weight: 650.76

Thapsigargin

CAS: 67526-95-8

• Formula: C₃₄H₅₀O₁₂
• Purity: By hplc: 98.95% (Typical Value in Batch COA)
• Color and Shape: white powder
• Molecular weight: 650.75g/mol

Thapsigargin

CAS: 67526-95-8

Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an …

• Formula: C₃₄H₅₀O₁₂
• Purity: 99.07% - 99.3%
• Color and Shape: Colourless Film
• Molecular weight: 650.75

Thapsigargin

CAS: 67526-95-8

• Formula: C₃₄H₅₀O₁₂
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: Colourless film
• Molecular weight: 650.75

Thapsigargin

CAS: 67526-95-8

Applications A widely used inhibitor of the ubiquitous sarco-endoplasmic reticulum Ca(2+)-ATPases in mammalian cells. It …

• Formula: C₃₄H₅₀O₁₂
• Color and Shape: Neat
• Molecular weight: 650.75

Thapsigargin

CAS: 67526-95-8

Potent inhibitor of SERCA ATPase

• Formula: C₃₄H₅₀O₁₂
• Purity: Min. 95%
• Color and Shape: Colourless Solid
• Molecular weight: 650.75 g/mol

Thapsigargin

CAS: 67526-95-8

• Formula: C₃₄H₅₀O₁₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 650.7536