CAS 6753-62-4

N-methyl-L-glutamic acid

Description:

N-methyl-L-glutamic acid is a derivative of the amino acid L-glutamic acid, characterized by the addition of a methyl group to the nitrogen atom of the amino group. This modification alters its properties and biological activity. The substance is a white crystalline solid that is soluble in water, reflecting its polar nature due to the presence of both carboxylic acid and amino functional groups. N-methyl-L-glutamic acid is known to act as a selective agonist for certain glutamate receptors, particularly the NMDA receptor, which plays a crucial role in synaptic plasticity and memory function in the central nervous system. Its chemical structure includes two carboxyl groups, contributing to its acidity, and it is classified as a non-proteinogenic amino acid. Due to its role in neurotransmission, N-methyl-L-glutamic acid is of interest in neuropharmacology and may have implications in the study of various neurological disorders. Safety data should be consulted for handling and potential toxicity, as with any chemical substance.

Formula: C₆H₁₁NO₄

Synonyms:

• N-Me-Glu-OH
• H-L-Meglu-Oh Hcl
• N-ALPHA-METHYL-L-GLUTAMIC ACID HYDROCHLORIDE
• H-L-MEGLU-OH HCL USP/EP/BP
• N-Methyl-L-glutamic aicd
• N-Mathyl-L-glutamic acid
• N-α-Methyl-L-glutamic acid hydrate
• L-Glutamic acid, N-methyl-
• N-METHYL-L-GLUTAMIC ACID HYDROCHLORIDE
• H-N-Me-Glu-OH
• N-Me-L-Glu-OH
• (2S)-2-(methylamino)pentanedioic acid
• N-ME-GLUTAMIC ACID
• H-MEGLU-OH
• N-Methyl-L-glutamic acid hydrochloride (1:1)
• N-ALPHA-METHYL-L-GLUTAMIC ACID
• N-ME-GLU-OH HCL
• N-Methyl-L-glutamic acid≥ 98% (HPLC)

N-Me-Glu-OH

CAS: 6753-62-4

Bachem ID: 4002660.

Formula: C₆H₁₁NO₄

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 161.16

Ref: 01-4002660

(S)-2-(Methylamino)pentanedioic acid

CAS: 6753-62-4

Formula: C₆H₁₁NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 161.1558

Ref: IN-DA006EV1

(S)-2-(Methylamino)pentanedioic acid

CAS: 6753-62-4

(S)-2-(Methylamino)pentanedioic acid

Purity: 97%

Molecular weight: 161.16g/mol

Ref: 54-OR1054688

N-Methyl-L-glutamic Acid

CAS: 6753-62-4

Formula: C₆H₁₁NO₄

Color and Shape: Neat

Molecular weight: 161.16

Ref: TR-N240115

N-Methyl-L-glutamic acid

CAS: 6753-62-4

N-Methyl-L-glutamic acid (NMG) is a metabolite of the amino acid L-glutamic acid. NMG is found in many tissues, and has been detected in plasma, cerebrospinal fluid, urine, and brain tissue. It also has been found in high concentrations in the brains of depressed patients. NMG is converted to n-methyl-d-aspartic acid (NMDA), which may be responsible for some of its effects on neurotransmitters. NMDA receptor antagonists are being investigated as treatments for depression and epilepsy. NMG is also involved in energy metabolism, as it can be converted to oxaloacetate by a number of enzymes. The enzyme activities for this conversion include glutamate carboxypeptidase II, glutamine synthase, glutamate dehydrogenase, glutamine synthetase and aspartate aminotransferase.

Formula: C₆H₁₁NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 161.16 g/mol

Ref: 3D-FM43099