CAS 67727-97-3
:.alpha.-MSH (11-13) (free acid)
Description:
.alpha.-MSH (11-13) (free acid), with the CAS number 67727-97-3, is a peptide derived from the melanocyte-stimulating hormone (MSH) family, specifically a fragment of the alpha-MSH molecule. This peptide consists of 3 amino acids, typically exhibiting biological activity related to pigmentation, appetite regulation, and energy homeostasis. It is characterized by its role in the central nervous system and peripheral tissues, where it interacts with melanocortin receptors. The free acid form indicates that it is not in a salt form, which can influence its solubility and stability. .alpha.-MSH (11-13) is often studied for its potential therapeutic applications, including its effects on skin pigmentation and its neuroprotective properties. In laboratory settings, it is typically synthesized through solid-phase peptide synthesis and can be analyzed using techniques such as mass spectrometry and high-performance liquid chromatography (HPLC) to confirm its purity and identity. Overall, this peptide represents a significant area of research in neurobiology and endocrinology.
Formula:C16H30N4O4
InChI:InChI=1/C16H30N4O4/c1-10(2)13(16(23)24)19-14(21)12-7-5-9-20(12)15(22)11(18)6-3-4-8-17/h10-13H,3-9,17-18H2,1-2H3,(H,19,21)(H,23,24)/t11-,12-,13-/m0/s1
SMILES:CC(C)[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCCN)N)O
Synonyms:- H-Lys-Pro-Val-OH
- L-lysyl-L-prolyl-L-valine
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Found 2 products.
Msh (11-13)
CAS:<p>Msh (11-13) is a bioactive chemical.</p>Formula:C16H30N4O4Color and Shape:SolidMolecular weight:342.43α-MSH (11-13) (free acid) acetate salt
CAS:<p>α-MSH (11-13) (free acid) acetate salt is a synthetic, nonsteroidal compound that binds to and activates α-melanocyte-stimulating hormone receptors. It has been used as an antiinflammatory agent in the treatment of inflammatory bowel disease and bowel disease. α-MSH (11-13) (free acid) acetate salt is also being studied as a contraceptive and an elastase inhibitor. This drug has shown some promise in the treatment of autoimmune diseases, such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, multiple sclerosis, and type 1 diabetes mellitus. It is thought that α-MSH (11-13) (free acid) acetate salt may inhibit the production of inflammatory cells by inhibiting leukocyte elastase activity.</p>Formula:C16H30N4O4Purity:Min. 95%Molecular weight:342.43 g/mol

