CAS 67746-43-4

dibenzyl N,N-diethylphosphoramidite

Description:

Dibenzyl N,N-diethylphosphoramidite is a chemical compound characterized by its phosphoramidite functional group, which is commonly used in organic synthesis, particularly in the field of nucleic acid chemistry. This compound features two benzyl groups and two ethyl groups attached to a phosphorus atom, contributing to its unique reactivity and stability. It typically appears as a colorless to pale yellow liquid or solid, depending on the specific conditions. The presence of the phosphoramidite moiety allows it to act as a versatile building block in the synthesis of oligonucleotides, where it serves as a phosphoramidite reagent for the formation of phosphodiester bonds. Its reactivity is influenced by the electron-donating properties of the ethyl groups and the steric hindrance provided by the benzyl groups. Dibenzyl N,N-diethylphosphoramidite is sensitive to moisture and should be handled under anhydrous conditions to prevent hydrolysis. Overall, its structural features make it an important reagent in synthetic organic chemistry and biochemistry.

Formula: C₁₈H₂₄NO₂P

InChI: InChI=1/C18H24NO2P/c1-3-19(4-2)22(20-15-17-11-7-5-8-12-17)21-16-18-13-9-6-10-14-18/h5-14H,3-4,15-16H2,1-2H3

SMILES: CCN(CC)P(OCc1ccccc1)OCc1ccccc1

Synonyms:

• Dibenzyl-N,N-diethyl Phosphoramidite
• Dibenzyl Diethylamidophosphite

Dibenzyl diethylphosphoramidite

CAS: 67746-43-4

Formula: C₁₈H₂₄NO₂P

Color and Shape: Liquid

Molecular weight: 317.3624

Ref: IN-DA003PBT

Dibenzyl diethylphosphoramidite

CAS: 67746-43-4

Formula: C₁₈H₂₄NO₂P

Molecular weight: 317.37

Ref: 7W-GK3907

Dibenzyl N,N-Diethylphosphoramidite, Technical Grade

Controlled Product

CAS: 67746-43-4

Applications A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perich, J.W., et al.: Synthesis, 142 (1988), Wong, C-H., et al.: J. Am. Chem. Soc., 115, 2260 (1993)

Formula: C₁₈H₂₄NO₂P

Color and Shape: Neat

Molecular weight: 317.36

Ref: TR-D417000