CAS 6779-87-9

Dihydrobiopterin

Description:

Dihydrobiopterin (DBH) is a naturally occurring pteridine derivative that plays a crucial role as a cofactor in various biological processes, particularly in the synthesis of neurotransmitters such as serotonin, dopamine, and norepinephrine. It is a key intermediate in the biosynthesis of tetrahydrobiopterin (BH4), which is essential for the activity of several enzymes, including phenylalanine hydroxylase and nitric oxide synthase. DBH is characterized by its relatively low molecular weight and its ability to participate in redox reactions, making it an important molecule in cellular metabolism. It is typically found in a reduced form and can be oxidized to form biopterin. Dihydrobiopterin is soluble in water and exhibits a range of biological activities, including antioxidant properties. Its deficiency can lead to various metabolic disorders, emphasizing its significance in human health. As a research compound, it is often studied for its potential therapeutic applications in neurological and psychiatric conditions.

Formula: C₉H₁₃N₅O₃

InChI: InChI=1S/C9H13N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3,6,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,6-/m0/s1

InChI key: InChIKey=FEMXZDUTFRTWPE-DZSWIPIPSA-N

SMILES: O=C1C2=C(NCC([C@H]([C@H](C)O)O)=N2)NC(N)=N1

Synonyms:

• 1,2-Propanediol, 1-(2-amino-7,8-dihydro-4-hydroxy-6-pteridinyl)-, <span class="text-smallcaps">L</span>-erythro-
• 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone
• 2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydropteridin-4(1H)-one
• 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydropteridin-4(1H)-one
• 4(1H)-Pteridinone, 2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-7,8-dihydro-
• 4(1H)-Pteridinone, 2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-, (S-(R*,S*))-
• 4(3H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-
• 7,8-Dihydro-<span class="text-smallcaps">L</span>-biopterin
• 7,8-Dihydrobiopterin
• <span class="text-smallcaps">L</span>-erythro-7,8-Dihydrobiopterin
• <span class="text-smallcaps">L</span>-erythro-Dihydrobiopterin
• Dihydrobiopterin
• L-erythro-Dihydrobiopterin
• L-erythro-q-Dihydrobiopterin
• Quinonoid dihydrobiopterin
• q-BH2

1-(2-Amino-4-hydroxy-7,8-dihydropteridin-7-yl)propane-1,2-diol

CAS: 6779-87-9

Formula: C₉H₁₃N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.2312

Ref: IN-DA005PPU

7,8-dihydro Biopterin

CAS: 6779-87-9

Formula: C₉H₁₃N₅O₃

Color and Shape: Yellow Solid

Molecular weight: 239.24

Ref: 4Z-B-353

7,8-Dihydro-L-biopterin

CAS: 6779-87-9

7,8-Dihydro-L-biopterin

Purity: ≥98%

Molecular weight: 239.23g/mol

Ref: 54-BUP14460

7,8-Dihydro-L-biopterin

CAS: 6779-87-9

7,8-Dihydro-L-biopterin is a kind of oxidation product of tetrahydrobiopterin.

Formula: C₉H₁₃N₅O₃

Purity: 98.97% - >99.99%

Color and Shape: Solid

Molecular weight: 239.23

Ref: TM-T19160

7,8-Dihydrobiopterin

CAS: 6779-87-9

Formula: C₉H₁₃N₅O₃

Molecular weight: 239.24

Ref: ST-EA-CP-S25002

7,8-Dihydro-L-biopterin-d3, 13C

Controlled Product

CAS: 6779-87-9

Formula: CC₈D₃H₁₀N₅O₃

Color and Shape: Neat

Molecular weight: 243.242

Ref: TR-D448522

7,8-Dihydro-biopterin

CAS: 6779-87-9

7,8-Dihydro-biopterin is a cofactor for the enzyme phenylalanine hydroxylase that converts phenylalanine to tyrosine. It is also an essential cofactor for the enzymes dopamine b-hydroxylase and aromatic amino acid decarboxylase, which are involved in the synthesis of neurotransmitters. 7,8-Dihydro-biopterin has been shown to regulate transcriptional activities by interacting with DNA polymerase alpha and beta. This interaction leads to changes in enzyme activities such as dihydrobiopterin reductase and biopterin oxidoreductase. Structural analysis of 7,8-dihydrobiopterin has shown that it contains a basic protein domain and a tetrahydrobiopterin domain. The basic protein domain interacts with some other proteins and is responsible for its stability.

Formula: C₉H₁₃N₅O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 239.23 g/mol

Ref: 3D-FD04487