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CAS 6780-38-7

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Phthalimidoacetyl chloride

Description:
Phthalimidoacetyl chloride, with the CAS number 6780-38-7, is an organic compound characterized by its acyl chloride functional group, which is derived from phthalimide. It typically appears as a white to off-white solid and is known for its reactivity, particularly in acylation reactions. This compound is often used as an intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. It is soluble in organic solvents such as dichloromethane and chloroform but is generally insoluble in water due to its hydrophobic nature. Phthalimidoacetyl chloride can release hydrochloric acid upon hydrolysis, making it a potential irritant. Safety precautions should be taken when handling this compound, as it can cause skin and eye irritation. Additionally, it should be stored in a cool, dry place away from moisture and incompatible substances. Overall, its unique chemical properties make it a valuable reagent in synthetic organic chemistry.
Formula:C10H6ClNO3
InChI:InChI=1S/C10H6ClNO3/c11-8(13)5-12-9(14)6-3-1-2-4-7(6)10(12)15/h1-4H,5H2
InChI key:InChIKey=RHZBRCQIKQUQHQ-UHFFFAOYSA-N
SMILES:O=C1C=2C(C(=O)N1CC(Cl)=O)=CC=CC2
Synonyms:
  • (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl chloride
  • (1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetyl chloride
  • 1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetyl chloride
  • 1,3-dihydro-1,3-dioxo-2h-isoindole-2-acetylchlorid
  • 2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)acetyl chloride
  • 2-(1,3-Dioxoisoindol-2-yl)acetyl chloride
  • 2-(1,3-Dioxoisoindolin-2-yl)acetyl chloride
  • 2-Isoindolineacetyl chloride, 1,3-dioxo-
  • 2-Phthalimidoacetyl chloride
  • 2-Phthalimidoylacetyl chloride
  • See more synonyms
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