CAS 67805-67-8
:8-bromoquinolin-2(1H)-one
Description:
8-Bromoquinolin-2(1H)-one is an organic compound characterized by its quinoline structure, which features a bromine atom at the 8-position and a ketone functional group at the 2-position. This compound typically appears as a solid and is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals due to its biological activity. The presence of the bromine atom can enhance the compound's reactivity and influence its interaction with biological targets. It is soluble in organic solvents, which makes it useful in various synthetic reactions. The compound may exhibit properties such as fluorescence, making it valuable in analytical chemistry and as a probe in biological studies. Additionally, its derivatives can be synthesized to explore a range of pharmacological activities, including antimicrobial and anticancer properties. As with many chemical substances, safety precautions should be observed when handling 8-bromoquinolin-2(1H)-one, as it may pose health risks if ingested or inhaled.
Formula:C9H6BrNO
InChI:InChI=1/C9H6BrNO/c10-7-3-1-2-6-4-5-8(12)11-9(6)7/h1-5H,(H,11,12)
SMILES:c1cc2ccc(nc2c(c1)Br)O
Synonyms:- 8-Bromo-2(1H)-quinolinone
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Found 4 products.
8-Bromoquinolin-2(1H)-one
CAS:Formula:C9H6BrNOPurity:98%Color and Shape:SolidMolecular weight:224.05408-Bromoquinolin-2(1H)-one
CAS:<p>8-Bromoquinolin-2(1H)-one</p>Formula:C9H6BrNOPurity:98%Color and Shape: peachy beige fine crystalline needlesMolecular weight:224.05404g/mol8-Bromoquinolin-2(1H)-one
CAS:<p>8-Bromoquinolin-2(1H)-one is an organic compound that inhibits the production of inflammatory substances in the body. It is a long-chain alkene and a synthetic substance that is used to prepare pharmaceuticals. 8-Bromoquinolin-2(1H)-one has been shown to have anti-cancer properties, as well as an inhibitory effect on inflammation. The drug is synthesized by reacting benzonitrile with bromine and ammonia in a reaction system. 8-Bromoquinolin-2(1H)-one inhibits the synthesis of prostaglandin E2 (PGE2) by inhibiting cyclooxygenase and lipoxygenase enzymes. It also binds with high affinity to the enzyme phospholipase A 2 (PLA 2 ), which results in a rapid hydrolysis of phospholipids and production of arachidonic acid, which leads to increased levels of PGE2.</p>Formula:C9H6BrNOPurity:Min. 95%Molecular weight:224.06 g/mol



