CAS 67869-62-9

gly-pro-arg-pro acetate

Description:

Gly-Pro-Arg-Pro acetate, identified by its CAS number 67869-62-9, is a synthetic peptide composed of four amino acids: glycine (Gly), proline (Pro), arginine (Arg), and another proline (Pro). This peptide exhibits characteristics typical of peptides, including a relatively low molecular weight and the ability to form specific secondary structures due to the presence of proline, which can induce turns in peptide chains. The acetate component indicates that the peptide is likely in its acetate salt form, which can enhance its solubility in aqueous solutions. Gly-Pro-Arg-Pro acetate may exhibit biological activity, potentially influencing processes such as cell signaling or modulation of physiological functions, although specific biological roles would depend on the context of its use. Its stability, solubility, and reactivity can be influenced by factors such as pH and temperature. As with many peptides, it may also be subject to enzymatic degradation, which is an important consideration in its application in research or therapeutic contexts.

Formula: C₁₈H₃₁N₇O₅

InChI: InChI=1/C18H31N7O5/c19-10-14(26)24-8-2-5-12(24)15(27)23-11(4-1-7-22-18(20)21)16(28)25-9-3-6-13(25)17(29)30/h11-13H,1-10,19H2,(H,23,27)(H,29,30)(H4,20,21,22)

SMILES: C(CC(C(=O)N1CCCC1C(=O)O)N=C(C1CCCN1C(=O)CN)O)CNC(=N)N

Synonyms:

• H-Gly-Pro-Arg-Pro-OH
• glycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-proline
• glycylprolyl-N~5~-(diaminomethylidene)ornithylproline
• Gly-Pro-Arg-Pro

H-Gly-Pro-Arg-Pro-OH

CAS: 67869-62-9

GPRP (H-2935) inhibits fibrinogen/thrombin clotting, though it is less active than its C-terminal amide GPRP-NH₂.

Formula: C₁₈H₃₁N₇O₅

Purity: 97.4%

Color and Shape: White

Molecular weight: 425.49

Ref: 01-4004545

GPRP

CAS: 67869-62-9

GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.

Formula: C₁₈H₃₁N₇O₅

Color and Shape: White To Off-White Powder

Molecular weight: 425.48

Ref: TM-T27419

H-Gly-Pro-Arg-Pro-OH

Controlled Product

CAS: 67869-62-9

H-Gly-Pro-Arg-Pro-OH is a sealant that has been shown to be effective in the treatment of bowel disease. It is a calcium binding compound that can be administered topically or systemically. H-Gly-Pro-Arg-Pro-OH has clinical relevance in vivo with human beings and exhibits ATP levels that are similar to those found in normal tissue. The surface glycoprotein of this compound has been shown to have an affinity for epidermal growth factor, which may play a role in inflammatory bowel disease. HGPAROH is activated by fibrinogen, which leads to its bound form being recognized by monoclonal antibody as well as the human serum proteins (e.g., albumin).

Formula: C₁₈H₃₁N₇O₅

Purity: Min. 95%

Molecular weight: 425.48 g/mol

Ref: 3D-INH-3797-PI

Fibrinolysis Inhibitng Factor

CAS: 67869-62-9

Fibrinolysis Inhibiting Factor is a surface glycoprotein that belongs to the group of human serum proteins. It has been shown to be involved in the pathogenesis of bowel diseases and is a target for dextran sulfate. Fibrinolysis inhibiting factor binds to the surfaces of cells and blocks blood coagulation by interfering with the conversion of fibrinogen into fibrin. The protein also binds calcium ions and prevents them from being deposited on cell surfaces, thereby preventing inflammatory reactions such as inflammation of the bowel. Fibrinolysis inhibiting factor has been shown to activate monoclonal antibodies in vitro, which may explain its effect on inflammatory bowel disease.

Formula: C₁₈H₃₁N₇O₅

Purity: Min. 95%

Molecular weight: 425.48 g/mol

Ref: 3D-FF73385