CAS 67910-12-7

11-Dehydro-TXB2

Description:

11-Dehydro-TXB2, with the CAS number 67910-12-7, is a metabolite of thromboxane A2, which is a potent vasoconstrictor and platelet aggregator. This compound is characterized by its role in the cardiovascular system, particularly in promoting platelet aggregation and influencing vascular tone. Structurally, it is a derivative of prostaglandin and features a unique cyclopentane ring with various functional groups that contribute to its biological activity. 11-Dehydro-TXB2 is typically found in biological fluids and is often measured as a biomarker for thromboxane synthesis and platelet activation. Its presence can indicate various physiological and pathological conditions, including cardiovascular diseases. The compound is also of interest in pharmacological research, particularly in the context of anti-thrombotic therapies. Overall, 11-Dehydro-TXB2 serves as an important indicator of thromboxane activity and has implications in both health and disease states.

Formula: C₂₀H₃₂O₆

InChI: InChI=1S/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+/m0/s1

InChI key: InChIKey=KJYIVXDPWBUJBQ-UHHGALCXSA-N

SMILES: C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)OC(=O)C[C@@H]1O

Synonyms:

• (5Z)-7-[(2R,3S,4S)-Tetrahydro-4-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6-oxo-2H-pyran-3-yl]-5-heptenoic acid
• 11-Dehydrothromboxane B₂
• 11-keto-Thromboxane B₂
• 5-Heptenoic acid, 7-((2R,3S,4S)-tetrahydro-4-hydroxy-2-((1E,3S)-3-hydroxy-1-octenyl)-6-oxo-2H-pyran-3-yl)-, (5Z)-
• 5-Heptenoic acid, 7-[(2R,3S,4S)-tetrahydro-4-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-6-oxo-2H-pyran-3-yl]-, (5Z)-
• 5-Heptenoic acid, 7-[tetrahydro-4-hydroxy-2-(3-hydroxy-1-octenyl)-6-oxo-2H-pyran-3-yl], [2R-[2α(1E,3S*),3β(Z),4β]]-
• Thromboxa-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9alpha,13E,15S)-
• Thromboxa-5,13-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S)-
• 11-Dehydrothromboxane B2

11-Dehydrothromboxane B2

CAS: 67910-12-7

Formula: C₂₀H₃₂O₆

Molecular weight: 368.47

Ref: 4Z-T-724

11-Dehydrothromboxane B2-d7

CAS: 67910-12-7

Formula: C₂₀H₂₅D₇O₆

Molecular weight: 375.51

Ref: 4Z-T-725

11-Dehydro Thromboxane B2 (85%)

CAS: 67910-12-7

Formula: C₂₀H₃₂O₆

Purity: 85%

Color and Shape: Neat

Ref: TR-D230555

11-Dehydro Thromboxane B2, 500ug/ml in Methyl Acetate

CAS: 67910-12-7

Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.  11-dehydro TXB2 is one of the main plasma metabolites of TXB2.The measurement of 11-dehydro thromboxane B2 can be used to assess the bronchoconstrictor response in experimental animals and humans. 11-Dehydro thromboxane B2 is also used as a marker for infectious diseases, including tuberculosis, malaria, and sepsis.Supplied as a solution in methyl acetate.

Formula: C₂₀H₃₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 368.46 g/mol

Ref: 3D-FD20950

11-Dehydrothromboxane B2

CAS: 67910-12-7

Formula: C₂₀H₃₂O₆

Molecular weight: 368.47

Ref: ST-EA-CP-T211003