CAS 6795-23-9

Aflatoxin M1

Description:

Aflatoxin M1 is a mycotoxin produced by the fungal species Aspergillus flavus and Aspergillus parasiticus, primarily found in contaminated dairy products, particularly milk from animals that have ingested aflatoxin B1. It is a secondary metabolite and is classified as a potent carcinogen, specifically associated with liver cancer in humans. Aflatoxin M1 is a polar compound, soluble in organic solvents like methanol and acetonitrile, but less soluble in water. Its chemical structure features a lactone ring and a furan moiety, contributing to its biological activity. The substance is regulated in many countries due to its toxicity and potential health risks, leading to strict limits on permissible levels in food and feed products. Detection methods often involve high-performance liquid chromatography (HPLC) coupled with fluorescence detection or mass spectrometry. Due to its stability, aflatoxin M1 can persist in food products, making monitoring and control essential in food safety practices.

Formula: C₁₇H₁₂O₇

InChI: InChI=1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1

InChI key: InChIKey=MJBWDEQAUQTVKK-IAGOWNOFSA-N

SMILES: O[C@]12C=3C4=C(C5=C(C(=O)O4)C(=O)CC5)C(OC)=CC3O[C@]1(OC=C2)[H]

Synonyms:

• (6AR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione
• (6aR,9aR)-2,3,6a,9a-Tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione
• (6aR-cis)-2,3,6a,9a-Tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dion
• (6aR-cis)-2,3,6a,9a-tetrahidro-9a-hidroxi-4-metoxiciclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopirano-1,11-diona
• (6aR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyranne-1,11-dione
• 1-Cyclopentene-1-carboxylic acid, 2-(3a,8a-dihydro-3a,4-dihydroxy-6-methoxyfuro[2,3-b]benzofuran-5-yl)-5-oxo-, δ-lactone
• 4-Hydroxyaflatoxin B1
• 9A-Hydroxy-4-Methoxy-2,3,6A,9A-Tetrahydrocyclopenta[C]Furo[3',2':4,5]Furo[2,3-H]Chromene-1,11-Dione
• AFM₁
• Aflatoxin M1
• Aflatoxin M₁
• Afm1
• Ccris 15
• Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-
• Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-, (6aR,9aR)-
• Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-, (6aR-cis)-
• Cyclopenta[c]furo[3′,2′:4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-, (6aR,9aR)-

Aflatoxin M1 0.5 µg/mL in Acetonitrile

Controlled Product

CAS: 6795-23-9

Formula: C₁₇H₁₂O₇

Color and Shape: Single Solution

Molecular weight: 328.27

Ref: 04-V10047550AL-0.5

Aflatoxin M1 0.5 µg/mL in Acetonitrile

Controlled Product

CAS: 6795-23-9

Formula: C₁₇H₁₂O₇

Color and Shape: Single Solution

Molecular weight: 328.27

Ref: 04-A10047550AL-0.5

Aflatoxin M1-13C-d3

CAS: 6795-23-9

Formula: C₁₆₁₃CH₉D₃O₇

Molecular weight: 332.29

Ref: 4Z-A-9512

Aflatoxin M1

CAS: 6795-23-9

Formula: C₁₇H₁₂O₇

Molecular weight: 328.28

Ref: 4Z-A-958

Aflatoxin M1

Controlled Product

CAS: 6795-23-9

Aflatoxin M1 is a mycotoxin that is produced by Aspergillus flavus and Aspergillus parasiticus. It has been shown to cause genotoxic activity in humans and carcinogenic potential. Aflatoxin M1 has also been shown to inhibit the growth of probiotic bacteria. The structural analysis of this substance has been performed using organic chemistry methods. Aflatoxin M1 causes DNA damage and inhibits protein synthesis, which leads to cell death. The optical sensor is used for detection of aflatoxins in milk samples and is based on the fluorescence properties of this compound. Electrochemical impedance spectroscopy (EIS) can be used for the analysis of matrices with aflatoxins, such as corn oil or peanut butter, due to its non-destructive nature.

Formula: C₁₇H₁₂O₇

Purity: Min. 95%

Molecular weight: 328.27 g/mol

Ref: 3D-FA17236

Aflatoxin M1

CAS: 6795-23-9

Formula: C₁₇H₁₂O₇

Molecular weight: 328.28

Ref: ST-EA-CP-A174006

Aflatoxin M1

CAS: 6795-23-9

Aflatoxin M1, a toxic metabolite of Aflatoxin B1, is produced by Aspergillus fungi, with a toxicity order: B1 > M1 > G1 > B2 > M2 > G2.

Formula: C₁₇H₁₂O₇

Color and Shape: Solid

Molecular weight: 328.276

Ref: TM-T13534

Aflatoxin M1

Controlled Product

CAS: 6795-23-9

Formula: C₁₇H₁₂O₇

Color and Shape: White

Molecular weight: 328.27

Ref: TR-A357500