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CAS 68-60-0

:

Tetrahydro-11-deoxycortisol

Description:
Tetrahydro-11-deoxycortisol, also known by its CAS number 68-60-0, is a steroid hormone that is a derivative of cortisol. It is characterized by its four saturated carbon rings, which is typical of steroid structures. This compound is primarily involved in the biosynthesis of corticosteroids and has been studied for its potential biological activities, including anti-inflammatory effects. Tetrahydro-11-deoxycortisol is soluble in organic solvents but has limited solubility in water, which is common for many steroid compounds. Its molecular structure includes hydroxyl groups that contribute to its reactivity and biological function. The compound is often used in research settings to understand steroid metabolism and the physiological roles of corticosteroids in the body. As with many steroids, it may exhibit varying degrees of potency and efficacy depending on its interaction with specific receptors. Safety and handling precautions are essential when working with this substance, as it may have biological effects that require careful consideration in laboratory settings.
Formula:C21H34O4
InChI:InChI=1S/C21H34O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h13-17,22-23,25H,3-12H2,1-2H3/t13-,14-,15-,16+,17+,19+,20+,21+/m1/s1
InChI key:InChIKey=UPTAPIKFKZGAGM-FAIYVORSSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]
Synonyms:
  • (3Alpha,5Beta)-3,17,21-Trihydroxypregnan-20-One
  • (3α,5β)-3,17,21-Trihydroxypregnan-20-one
  • 11-Deoxytetrahydrocortisol
  • 3,17,21-Trihydroxypregnan-20-One
  • 3alpha,17,21-Trihydroxy-5beta-pregnan-20-one
  • 3α,17,21-Trihydroxy-5β-pregnan-20-one
  • 3α,17α,21-Trihydroxy-5β-pregnan-20-one
  • 3α,17α,21-Trihydroxy-5β-pregnane-20-one
  • 5β-Pregnan-20-one, 3α,17,21-trihydroxy-
  • Cortexolone, tetrahydro-
  • See more synonyms
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Found 3 products.
  • Tetrahydro-11-deoxy Cortisol
    TRC
    + Info

    Tetrahydro-11-deoxy Cortisol

    CAS:

    Applications A metabolite of Cortisol (H714615).
    References Aguilera, R., et al.: Clin. Chem., 47, 292 (2001), Pujos, E., et al.: Anal. Bioanal. Chem., 381, 244 (2005), Flenker, U., et al.: Steroids, 73, 408 (2008),

    Formula:C21H34O4
    Color and Shape:Neat
    Molecular weight:350.49

    Ref: TR-T293390

    5mg
    276.00€
    10mg
    327.00€
    25mg
    384.00€
  • Tetrahydro-11-deoxy Cortisol-d5
    TRC
    + Info

    Tetrahydro-11-deoxy Cortisol-d5

    Controlled Product
    CAS:

    Applications A labelled metabolite of Cortisol (H714615).
    References Aguilera, R., et al.: Clin. Chem., 47, 292 (2001), Pujos, E., et al.: Anal. Bioanal. Chem., 381, 244 (2005), Flenker, U., et al.: Steroids, 73, 408 (2008),

    Formula:C21D5H29O4
    Color and Shape:Neat
    Molecular weight:355.52

    Ref: TR-T293392

    5mg
    3,152.00€
  • Tetrahydro-11-deoxy cortisol
    Biosynth
    + Info

    Tetrahydro-11-deoxy cortisol

    Controlled Product
    CAS:
    Tetrahydro-11-deoxy cortisol (THDOC) is a synthetic corticosteroid that is used in the treatment of proliferative diabetic retinopathy. It has been shown to reduce the severity of retinal neovascularization in experimental models. THDOC has a hydroxyl group at position 11 and a double bond between C-11 and C-12, which are not present in natural cortisol. The body mass index (BMI) of women with high values for THDOC is correlated with the prevalence of adrenocortical carcinoma. This correlation suggests that THDOC may be useful as a diagnostic marker for this type of cancer.
    Formula:C21H34O4
    Purity:Min. 95 Area-%
    Color and Shape:White Off-White Powder
    Molecular weight:350.49 g/mol

    Ref: 3D-FT28089

    5mg
    215.00€
    10mg
    343.00€
    25mg
    582.00€
    50mg
    933.00€
    100mg
    1,119.00€