CAS 68-89-3
:Dipyrone
Description:
Dipyrone, also known as metamizole, is a non-opioid analgesic and antipyretic agent commonly used for pain relief and fever reduction. It is classified as a pyrazolone derivative and is known for its potent analgesic properties. Dipyrone is typically administered in its sodium salt form, which enhances its solubility in water. The compound is characterized by its ability to inhibit prostaglandin synthesis, thereby reducing pain and inflammation. It is often used in clinical settings for severe pain management, particularly when other analgesics are ineffective. However, dipyrone has been associated with serious side effects, including agranulocytosis, a potentially life-threatening decrease in white blood cell count, which has led to its restricted use in some countries. The substance is generally well-absorbed when administered orally or intravenously, and its effects can be rapid, making it a valuable option in acute pain scenarios. Despite its efficacy, healthcare providers must weigh the benefits against the risks when considering dipyrone for patient treatment.
Formula:C13H16N3NaO4S
InChI:InChI=1/C13H19N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8,10,12H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/rC13H18N3NaO4S/c1-10-12(14(2)9-22(19,20)21-17)13(18)16(15(10)3)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3
InChI key:InChIKey=CEOUXRNZHGKECQ-UHFFFAOYSA-N
SMILES:O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2.[Na]
Synonyms:- Algocalmin
- Algopyrin
- Amoloid HV
- Amoloid LV
- Anador
- Analgin
- Analgin DAB10
- Analgine
- Andolor
- Arpf
- Collatex A/RE
- Collatex Arm Extra
- CollatexA/RE Extra
- Conmel
- Diprofarn
- Dipyrone,hydrate
- Duckammon
- E 403
- Gifaril
- Kimica Algin NH
- Kimitsu Algin NH
- Lisador
- Manutex PC-MV
- Metamizol
- Metamizole
- Metamizole Sodium
- Metamizole sodium salt
- Metapyrin
- Methamizole sodium
- Methampyrone
- Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt
- Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1)
- Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt
- Methylmelubrin
- Metilon
- Narone
- Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
- Neo-melubrine
- Noramidopyrine methanesulfonate sodium
- Noramidopyrine methanesulfonate sodium salt
- Noraminophenazone methanesulfonate sodium salt
- Noraminophenazone sodium mesylate
- Novalgetol
- Novalgin
- Novamidazophen
- Novaminophenazone
- Novaminsulfone
- Novaminsulfone sodium
- Novaminsulfonium
- Novaminsulfonum
- Noveltex
- Optalgin
- Pharmalgine
- Protamon S
- Pyralgine
- Pyretin
- Pyretin (pharmaceutical)
- Restriva
- Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate
- Sodium (antipyrinylmethylamino)methanesulfonate
- Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
- Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
- Sodium metamizole
- Sodium noramidopyrine methanesulfonate
- Sodium novaminsulfonate
- Sulpin
- Sulpyrin
- Sulpyrine
- [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium
- [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
- [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt
- [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium
- [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio
- sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
- sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
- Dipyrone
- BENZALAGEN
- (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt
- SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE
- 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
- (antipyrinylmethylamino)methanesulfonicacidsodiumsalt
- 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
- dipyron
- LABOTEST-BB LT00771955
- (antipyrinylmethylamino)-methanesulfonicacisodiumsalt
- DIPYRONE SODIUM
- 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
- METAMIZOL SODIUM
- SODIUM DIPYRONE
- See more synonyms
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Found 11 products.
Metamizole Sodium Salt
CAS:Formula:C13H16N3NaO4SPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:333.34Metamizole sodium
CAS:Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.Formula:C13H16N3NaO4SPurity:99.52%Color and Shape:White Or Almost White Crystal PowderMolecular weight:333.34Metamizole Sodium Salt (Dipyrone)
CAS:Formula:C13H16N3O4S·NaColor and Shape:White To Off-White SolidMolecular weight:310.35 22.99Metamizol sodium
CAS:Controlled ProductFormula:C13H16N3O4S·NaColor and Shape:NeatMolecular weight:333.34Dipyrone
CAS:Controlled Product<p>Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.<br>References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),<br></p>Formula:C13H16N3O4S·NaColor and Shape:WhiteMolecular weight:333.34Dipyrone-d3
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.<br>References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);<br></p>Formula:C13H13D3N3NaO4SColor and Shape:Off-WhiteMolecular weight:336.36Dipyrone
CAS:<p>Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.</p>Formula:C13H16N3NaO4SPurity:Min. 95%Color and Shape:White SolidMolecular weight:333.34 g/mol
