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CAS 68-91-7

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Trimethaphan camsylate

Description:
Trimethaphan camsylate is a chemical compound primarily used as a ganglionic blocker in medical applications, particularly for managing hypertension during surgical procedures. It is classified as a quaternary ammonium compound, which means it contains a positively charged nitrogen atom bonded to four carbon-containing groups. This structure contributes to its pharmacological properties, allowing it to inhibit neurotransmission in the autonomic nervous system. Trimethaphan camsylate is typically administered intravenously due to its poor oral bioavailability. The compound is known for its rapid onset of action and relatively short duration, making it suitable for acute management of blood pressure. In terms of physical characteristics, it is usually presented as a white to off-white crystalline powder, soluble in water, which facilitates its use in clinical settings. Safety and efficacy profiles are well-documented, but like all medications, it may have side effects and contraindications that must be considered during use.
Formula:C22H25N2OS·C10H15O4S
InChI:InChI=1S/C22H25N2OS.C10H16O4S/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h1-6,8-11,19-21H,7,12-16H2;7H,3-6H2,1-2H3,(H,12,13,14)/q+1;/p-1/t;7-,10-/m.1/s1
InChI key:InChIKey=HALWUDBBYKMYPW-STOWLHSFSA-M
SMILES:C(S(=O)(=O)[O-])[C@@]12C(C)(C)[C@@](CC1=O)(CC2)[H].C(N1C2C(N(CC3=CC=CC=C3)C1=O)C[S+]4C2CCC4)C5=CC=CC=C5
Synonyms:
  • Thieno[1′,2′:1,2]thieno[3,4-d]imidazol-5-ium, decahydro-2-oxo-1,3-bis(phenylmethyl)-, salt with (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1)
  • Trimethaphan, camphorsulfonate
  • Thieno[1′,2′:1,2]thieno[3,4-d]imidazol-5-ium, decahydro-2-oxo-1,3-bis(phenylmethyl)-, salt with (1S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1)
  • 10-Bornanesulfonic acid, 2-oxo-, ion(1-), (+)-, (+)-1,3-dibenzyldecahydro-2-oxothieno[1′,2′:1,2]thieno[3,4-d]imidazol-5-ium
  • Thieno[1′,2′:1,2]thieno[3,4-d]imidazol-5-ium, octahydro-2-oxo-1,3-bis(phenylmethyl)-, (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate (1:1)
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