CAS 68-94-0

Hypoxanthine

Description:

Hypoxanthine is a purine base that plays a crucial role in the metabolism of nucleotides. It is a naturally occurring compound found in various biological systems, particularly as a product of adenine and guanine metabolism. Hypoxanthine has the molecular formula C5H4N4O and a molar mass of approximately 136.1 g/mol. It is characterized by its white to off-white crystalline appearance and is soluble in water, with limited solubility in organic solvents. Hypoxanthine is involved in several biochemical pathways, including the purine salvage pathway, where it is converted into inosine monophosphate (IMP) by the enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). This compound is also a precursor to uric acid, which is significant in the context of gout and other metabolic disorders. Additionally, hypoxanthine has been studied for its potential roles in cellular signaling and as an antioxidant. Its CAS number is 68-94-0, which uniquely identifies it in chemical databases.

Formula: C₅H₄N₄O

InChI: InChI=1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

InChI key: InChIKey=FDGQSTZJBFJUBT-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC=N1)N=CN2

Synonyms:

• 1,7-Dihydro-6H-purin-6-one
• 1,9-Dihydro-6H-purin-6-one
• 1,9-Dihydro-purin-6-one
• 1H,7H-Hypoxanthine
• 1H,9H-Hypoxanthine
• 1H-Purin-6(9H)-one
• 3,5-dihydro-6H-purin-6-one
• 3,7-dihydro-6H-purin-6-one
• 3H-Purin-6-ol
• 6-Hydroxy-1H-purine
• 6-Hydroxypurine
• 6-Oxopurine
• 6H-Purin-6-one, 1,7-dihydro-
• 6H-Purin-6-one, 1,9-dihydro-
• 9H-Purin-6(1H)-one
• 9H-Purin-6-ol
• Hypoxanthine 6-Hydroxypurine
• Hypoxanthine enol
• Nsc 129419
• Nsc 14665
• Purin-6(1H)-on
• Purin-6(3H)-one
• Purin-6-ol
• Sarcine
• Sarkin
• Sarkine
• purin-6(1H)-ona
• purin-6(1H)-one
• purine-6(1H)-one

Hypoxanthine

CAS: 68-94-0

Formula: C₅H₄N₄O

Purity: >98.0%(HPLC)(E)

Color and Shape: White to Light yellow to Light red powder to crystal

Molecular weight: 136.11

Ref: 3B-H0311

Hypoxanthine, 99%

CAS: 68-94-0

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies alon

Formula: C₅H₄N₄O

Purity: 99%

Color and Shape: Powder or lumps, White to pale cream

Molecular weight: 136.11

Ref: 02-A11481

MERCAPTOPURINE IMPURITY A CRS

CAS: 68-94-0

MERCAPTOPURINE IMPURITY A CRS

Ref: 41-Y0002147

DIDANOSINE IMPURITY A CRS

CAS: 68-94-0

DIDANOSINE IMPURITY A CRS

Ref: 41-Y0000441

Didanosine Related Compound A

CAS: 68-94-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₅H₄N₄O

Color and Shape: Off-White White Powder

Molecular weight: 136.03851

Ref: 45-1191226

1,7-Dihydro-6H-purine-6-one

CAS: 68-94-0

Formula: C₅H₄N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 136.1115

Ref: IN-DA00350E

Hypoxanthine

CAS: 68-94-0

Hypoxanthine, a purine derivative, is a metabolite in nucleic acid synthesis and oxidizes to uric acid via xanthine.

Formula: C₅H₄N₄O

Purity: 98.39% - 99.86%

Color and Shape: Solid

Molecular weight: 136.1115

Ref: TM-T1362

Azathioprine EP Impurity F (Didanosine EP Impurity A, Didanosine USP Related Compound A, Hypoxanthine)

CAS: 68-94-0

Formula: C₅H₄N₄O

Molecular weight: 136.11

Ref: 4Z-A-154020

Hypoxanthine

CAS: 68-94-0

Hypoxanthine

Formula: C₅H₄N₄O

Purity: ≥98%

Molecular weight: 136.11

Ref: 54-BUP16572

Hypoxanthine

CAS: 68-94-0

Formula: C₅H₄N₄O

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 136.11

Ref: 7W-GE9204

Hypoxanthine (Standard)

CAS: 68-94-0

Hypoxanthine (Standard) is natural purine derivative acting as key intermediate in purine metabolism.

Formula: C₅H₄N₄O

Molecular weight: 136.1115

Ref: TM-TMSM-1344

Didanosine EP Impurity A (Azathioprine EP Impurity F)

Controlled Product

CAS: 68-94-0

Formula: C₅H₄N₄O

Color and Shape: Neat

Molecular weight: 136.11

Ref: 86-MM1047.01

Hypoxanthine

CAS: 68-94-0

Formula: C₅H₄N₄O

Purity: 95%~99%

Molecular weight: 136.114

Ref: BP-BP3203

Hypoxanthine

Controlled Product

CAS: 68-94-0

Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals
References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),

Formula: C₅H₄N₄O

Color and Shape: Neat

Molecular weight: 136.11

Ref: TR-H998500

Hypoxanthine

CAS: 68-94-0

1,9-Dihydro-6H-purin-6-one

Formula: C₅H₄N₄O

Purity: 98%

Molecular weight: 136.11

Ref: IN-DG8644

Hypoxanthine

CAS: 68-94-0

Hypoxanthine

Formula: C₅H₄N₄O

Purity: 98%

Color and Shape: Solid-Powder

Molecular weight: 136.11146

Ref: 54-OR0545

Hypoxanthine

CAS: 68-94-0

Hypoxanthine is a nucleoside that is found in human cells. It is synthesized from guanine by the enzyme, xanthine oxidoreductase. Hypoxanthine is also produced from xanthine by adenosine deaminase and converted back to xanthine, which can then be reused for DNA synthesis. Hypoxanthine has been shown to inhibit the growth of photosynthetic bacteria, such as Rhodopseudomonas viridis and Rhodobacter sphaeroides. This inhibition may be due to an equilibrative nucleotide effect on the folate receptor. The x-ray diffraction data collected from the chrysanthemum flower (a source of hypoxanthine) showed that hypoxanthine has a calcium salt structure.

Formula: C₅H₄N₄O

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 136.11 g/mol

Ref: 3D-FH02949

Hypoxanthin-15N4

CAS: 68-94-0

Formula: C₅H₄N₄O

Color and Shape: Solid

Molecular weight: 136.11

Ref: BE-MN-8146

Hypoxanthine

CAS: 68-94-0

Formula: C₅H₄N₄O

Color and Shape: Solid

Molecular weight: 136.11

Ref: BE-BePure-23456

Hypoxanthine

CAS: 68-94-0

Formula: C₅H₄N₄O

Color and Shape: Solid

Molecular weight: 136.11

Ref: BE-RMCA349019