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CAS 6801-40-7

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Magnocurarine

Description:
Magnocurarine is a chemical compound classified as a neuromuscular blocking agent, primarily derived from the plant Chondrodendron tomentosum. It acts as a competitive antagonist at the neuromuscular junction, specifically targeting nicotinic acetylcholine receptors, which leads to muscle paralysis. This substance is characterized by its potency and relatively short duration of action, making it useful in surgical settings for facilitating intubation and providing muscle relaxation during procedures. Magnocurarine is structurally related to other alkaloids and exhibits a complex molecular structure that contributes to its pharmacological effects. It is important to note that, like other neuromuscular blockers, magnocurarine requires careful monitoring during administration due to potential respiratory depression and the need for supportive ventilation. Its use is typically restricted to clinical environments where appropriate medical supervision is available. Safety and efficacy profiles are critical considerations, and it is essential to adhere to established guidelines when utilizing this compound in medical practice.
Formula:C19H24NO3
InChI:InChI=1S/C19H23NO3/c1-20(2)9-8-14-11-19(23-3)18(22)12-16(14)17(20)10-13-4-6-15(21)7-5-13/h4-7,11-12,17H,8-10H2,1-3H3,(H-,21,22)/p+1/t17-/m1/s1
InChI key:InChIKey=CLWOXNLVWMXBRD-QGZVFWFLSA-O
SMILES:C([C@@H]1C=2C(=CC(OC)=C(O)C2)CC[N+]1(C)C)C3=CC=C(O)C=C3
Synonyms:
  • (1R)-1,2,3,4-Tetrahydro-7-hydroxy-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2,2-dimethylisoquinolinium
  • (1R)-1-[(4-Hydroxyphenyl)methyl]-6-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-7-ol
  • (R)-Magnocurarine
  • <span class="text-smallcaps">D</span>-(-)-Magnocurarine
  • Isoquinolinium, 1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2,2-dimethyl-, (1R)-
  • Isoquinolinium, 1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2,2-dimethyl-, (R)-
  • Magnocurarine
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Found 5 products.