CAS 68011-67-6

3-Hydroxycarbamazepine

Description:

3-Hydroxycarbamazepine is a chemical compound that is a derivative of carbamazepine, which is primarily used as an anticonvulsant and mood-stabilizing drug. This substance is characterized by the presence of a hydroxyl group (-OH) at the third position of the carbamazepine structure, which influences its pharmacological properties. It is typically a white to off-white solid and is soluble in organic solvents, with limited solubility in water. The compound exhibits a range of biological activities, including potential anticonvulsant effects, and is of interest in pharmacological research for its role in the metabolism of carbamazepine. Its molecular structure includes a dibenzazepine core, which is common among many antiepileptic drugs. The presence of the hydroxyl group may enhance its interaction with biological targets, potentially affecting its efficacy and safety profile. As with many pharmaceutical compounds, understanding its characteristics is crucial for evaluating its therapeutic potential and implications in drug development.

Formula: C₁₅H₁₂N₂O₂

InChI: InChI=1S/C15H12N2O2/c16-15(19)17-13-4-2-1-3-10(13)5-6-11-7-8-12(18)9-14(11)17/h1-9,18H,(H2,16,19)

InChI key: InChIKey=QQCFBZCATDIWTH-UHFFFAOYSA-N

SMILES: C(N)(=O)N1C=2C(C=CC=3C1=CC=CC3)=CC=C(O)C2

Synonyms:

• 3-Hydroxycarbamazepine
• 3-Hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
• 5H-Dibenz[b,f]azepine-5-carboxamide, 3-hydroxy-

3-Hydroxy Carbamazepine

CAS: 68011-67-6

Formula: C₁₅H₁₂N₂O₂

Molecular weight: 252.28

Ref: 4Z-O-0620

3-Hydroxy Carbamazepine

CAS: 68011-67-6

Applications A metabolite of Carbamazepine (C175840).
References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),

Formula: C₁₅H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 252.27

Ref: TR-H884105

3-Hydroxy carbamazepine

CAS: 68011-67-6

3-Hydroxy carbamazepine is a reactive, water soluble compound with a molecular weight of 197.3 g/mol. It is the major metabolite of carbamazepine, which is an anticonvulsant drug used to treat epilepsy and nerve pain. 3-Hydroxy carbamazepine has been detected in urine samples of women using this medication and it has been shown that it can be eliminated from the body through the kidneys. 3-Hydroxy carbamazepine is also found in wastewater treatment plants, where it may act as a chemical inhibitor for biological treatment processes. This compound has been studied for its toxicity and found to have both acute and chronic effects, including neurotoxicity and mutagenicity.

Formula: C₁₅H₁₂N₂O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 252.27 g/mol

Ref: 3D-FH23934