CAS 68059-94-9

D-PYR-D-PHE-D-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2

Description:

The chemical substance with the name "D-PYR-D-PHE-D-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2" and CAS number "68059-94-9" is a synthetic peptide that consists of a sequence of amino acids, including D-Pyrrolidine (D-PYR), D-Phenylalanine (D-PHE), D-Tryptophan (D-TRP), Serine (SER), Tyrosine (TYR), Leucine (LEU), Arginine (ARG), Proline (PRO), and Glycine (GLY), with a C-terminal amide group (NH2). This peptide is characterized by its incorporation of D-amino acids, which can enhance stability against enzymatic degradation compared to their L-counterparts. The presence of various amino acids contributes to its potential biological activity, possibly influencing neuropeptide signaling or receptor interactions. Such peptides are often studied for their roles in pharmacology and biochemistry, particularly in the context of drug design and therapeutic applications. The specific arrangement of amino acids can impart unique properties, making it a subject of interest in research related to peptide synthesis and function.

Formula: C₆₇H₈₄N₁₆O₁₃

InChI: InChI=1/C67H84N16O13/c1-37(2)28-49(59(89)76-48(18-10-26-71-67(69)70)66(96)83-27-11-19-55(83)65(95)74-35-56(68)86)77-62(92)52(31-40-33-72-45-16-8-6-14-43(40)45)80-61(91)51(30-39-20-22-42(85)23-21-39)79-64(94)54(36-84)82-63(93)53(32-41-34-73-46-17-9-7-15-44(41)46)81-60(90)50(29-38-12-4-3-5-13-38)78-58(88)47-24-25-57(87)75-47/h3-9,12-17,20-23,33-34,37,47-55,72-73,84-85H,10-11,18-19,24-32,35-36H2,1-2H3,(H2,68,86)(H,74,95)(H,75,87)(H,76,89)(H,77,92)(H,78,88)(H,79,94)(H,80,91)(H,81,90)(H,82,93)(H4,69,70,71)/t47-,48+,49+,50-,51+,52-,53-,54+,55+/m1/s1

Synonyms:

• (D-Pyr1,D-Phe2,D-Trp3
• [D-PGLU1, D-PHE2, D-TRP3,6]-LH-RH
• [D-PYROGLU1,D-PHE2,D-TRP3,6]-LH-RH
• pglu(1)-phe(2)-trp(3,6)-lhr
• D-PYR-D-PHE-D-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
• [D-PYR1, D-PHE2, D-TRP3,6]-LH-RH (HUMAN)
• (D-PYR1,D-PHE2,D-TRP3,6)-LHRH
• D-PYROGLU-D-PHE-D-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-NH2
• D-pglu1,D-phe2,D-trp3,6-luteinizing*hormone relea
• [DGLP1,DPHE2,DTRP3,6]-LUTEINIZING HORMONE-RELEASING HORMONE
• Glycinamide, 5-oxo-D-prolyl-D-phenylalanyl-D-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolyl- (9CI)
• [D-PYR1, D-PHE2, D-TRP3,6]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN)
• (D-PYR1,D-PHE2,D-TRP3,6)-LUTEINIZING HORMONE-RELEASING HORMONE
• DGLP-DPHE-DTRP-SER-TYR-DTRP-LEU-ARG-PRO-GLY-NH2
• (D-PYR1,D-PHE2,D-TRP3,6)-GONADOTROPIN-RELEASING HORMONE
• D-PGLU1,D-PHE2,D-TRP3,6-LUTEINIZING*HORM ONE RELEASI
• [DGLP1,DPHE2,DTRP3,6]-LH-RH
• (D-PYR1,D-PHE2,D-TRP3,6)-LUTEINIZING HORMONE-RELEASING FACTOR
• LHRH, pGlu(1)-Phe(2)-Trp(3,6)-
• (D-Pyr1,D-Phe2,D-Trp3'6)-LHRH
• LHRH, D-pglu(1)-D-phe(2)-D-trp(3,6)-
• 1-Pyr-2-phe-3,6-trp-LHRH
• GNRH, pglu(1)-phe(2)-trp(3,6)-
• Gpt-LHRH
• Luteinizing hormone-releasing factor, 1-(5-oxo-D-proline)-2-D-phenylalanine-3-D-tryptophan-6-D-tryptophan-

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH

CAS: 68059-94-9

[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a synthetic LHRH analog and a GnRH receptor antagonist.

Formula: C₆₇H₈₄N₁₆O₁₃

Color and Shape: Solid

Molecular weight: 1321.48

Ref: TM-T76350