Substance P fragment 1-7, with the CAS number 68060-49-1, is a peptide derived from substance P, which is a neuropeptide involved in pain perception and inflammatory processes. This fragment consists of the first seven amino acids of the full substance P molecule, specifically functioning as a neurokinin. It exhibits characteristics typical of neuropeptides, including a relatively small molecular size and the ability to interact with neurokinin receptors, particularly the NK1 receptor. The fragment is known for its role in modulating pain and stress responses, as well as influencing various physiological functions such as mood regulation and gastrointestinal activity. Its structure includes a sequence of amino acids that contribute to its biological activity, and it is often studied in the context of neurobiology and pharmacology. Due to its specific interactions and effects, substance P fragment 1-7 is of interest in research related to pain management and neurogenic inflammation.

substance P fragment 1-7

68060-49-1: Substance P fragment 1-7, with the CAS number 68060-49-1, is a peptide derived from substance P, which is a neuropeptide involved in pain perception and inflammatory processes. This fragment consists of the first seven amino acids of the full substance P molecule, specifically functioning as a neurokinin. It exhibits characteristics typical of neuropeptides, including a relatively small molecular size and the ability to interact with neurokinin receptors, particularly the NK1 receptor. The fragment is known for its role in modulating pain and stress responses, as well as influencing various physiological functions such as mood regulation and gastrointestinal activity. Its structure includes a sequence of amino acids that contribute to its biological activity, and it is often studied in the context of neurobiology and pharmacology. Due to its specific interactions and effects, substance P fragment 1-7 is of interest in research related to pain management and neurogenic inflammation.

This amino-terminal fragment of substance P exerts depressor and bradycardic effects when applied to the nucleus tractus solitarius. It was also shown that this fragment, contrary to substance P, may reduce signs of opioid withdrawal in mice.

Substance P (1-7)

Substance P Fragment 1-7

Substance P(1-7) is a bioactive metabolite of tachykinin SP with anti-inflammatory and analgesic properties.

CAS 68060-49-1

substance P fragment 1-7

Substance P (1-7)

Ref: 01-4019809

Substance P Fragment 1-7

Ref: IN-DA00ILPK

Substance P(1-7)

Ref: TM-T7396