CAS 6809-52-5

Teprenone

Description:

Teprenone, also known as geranylgeranylacetone, is a synthetic compound primarily recognized for its role in promoting gastric mucosal protection and healing. It is classified as a terpenoid and is characterized by its ability to enhance the production of mucosal protective factors, thereby aiding in the prevention and treatment of gastric ulcers. Teprenone exhibits anti-inflammatory properties and has been studied for its potential benefits in various gastrointestinal disorders. The compound is typically administered orally and is well-absorbed in the gastrointestinal tract. Its mechanism of action involves the stimulation of mucosal cell proliferation and the enhancement of blood flow to the gastric mucosa. Additionally, Teprenone has been investigated for its potential neuroprotective effects and its role in various other therapeutic areas. As with any pharmaceutical agent, it is essential to consider its pharmacokinetics, potential side effects, and interactions with other medications when evaluating its use in clinical settings.

Formula: C₄₆H₇₆O₂

InChI: InChI=1/C23H38O/c1-19(2)11-7-12-20(3)13-8-14-21(4)15-9-16-22(5)17-10-18-23(6)24/h11,13,15,17H,7-10,12,14,16,18H2,1-6H3/b20-13+,21-15+,22-17+

InChI key: InChIKey=HUCXKZBETONXFO-UHFFFAOYSA-N

SMILES: C(CCC=C(CCC=C(C)C)C)(=CCCC(=CCCC(C)=O)C)C

Synonyms:

• (5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
• 5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-
• 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
• 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one, mixture of (5E,9E,13E) and (5Z,9E,13E) isomers
• E 0671
• E 36U31
• Geranylgeranylacetone
• Selbex
• Teprenona
• Teprenona [INN-Spanish]
• Teprenonum
• Teprenonum [INN-Latin]
• Unii-S8S8451A4O
• Teprenone
• Teprenone
• Tetraprenylacetone
• 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetren-2-one

Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers]

CAS: 6809-52-5

Formula: C₂₃H₃₈O

Purity: >95.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 330.56

Ref: 3B-T2701

TEPRENONE

CAS: 6809-52-5

Formula: C₂₃H₃₈O

Purity: 95%

Color and Shape: Liquid

Molecular weight: 330.5472

Ref: IN-DA003UI4

Teprenone

CAS: 6809-52-5

Teprenone

Purity: ≥98%

Molecular weight: 330.55g/mol

Ref: 54-BUP14911

Teprenone

CAS: 6809-52-5

Formula: C₂₃H₃₈O

Molecular weight: 330.55

Ref: 7W-GP5866

Teprenone

CAS: 6809-52-5

Formula: C₂₃H₃₈O

Purity: 95%~99%

Molecular weight: 330.556

Ref: BP-BP2100

Teprenone

CAS: 6809-52-5

Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).

Formula: C₂₃H₃₈O

Purity: 99.1% - 99.96%

Color and Shape: Solid

Molecular weight: 330.55

Ref: TM-T5008

Teprenone RS

CAS: 6809-52-5

Color and Shape: Colorless To Pale Yellow Liquid Clear Oily Liquid

Ref: 2K-1086200021

Teprenone

Controlled Product

CAS: 6809-52-5

Applications An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981), Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987),

Formula: C₂₃H₃₈O

Color and Shape: Neat

Molecular weight: 330.55

Ref: TR-T103500