CAS 6811-55-8

Dioleoyl-phosphatidyl-serine

Description:

Dioleoyl-phosphatidyl-serine (DOPS) is a phospholipid that plays a crucial role in cellular membranes, particularly in the context of cell signaling and membrane dynamics. It is characterized by its two oleoyl fatty acid chains, which contribute to its fluidity and flexibility in lipid bilayers. The presence of the serine head group imparts a net negative charge to the molecule, influencing its interactions with proteins and other membrane components. DOPS is often utilized in research and biotechnological applications, including the formulation of liposomes for drug delivery and as a component in membrane models to study protein-membrane interactions. Its amphiphilic nature allows it to self-assemble into bilayers, making it essential for maintaining membrane integrity and functionality. Additionally, DOPS is involved in various biological processes, such as apoptosis and cell signaling pathways, highlighting its importance in both physiological and pathological contexts. Overall, DOPS is a significant phospholipid with diverse applications in biochemistry and molecular biology.

Formula: C₄₂H₇₈NO₁₀P

InChI: InChI=1/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1

Synonyms:

• O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine
• sodium O-[({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)phosphinato]-L-serine
• L-ALPHA-PHOSPHATIDYL-L-SERINE, DIOLEOYL SODIUM SALT
• 1,2-Dioleoyl-sn-glycerol 3-phosphoserine
• 18:1 PS (SODIUM SALT)
• 1,2-DI-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT
• DOPS
• 1,2-Dioleoyl-sn-glycero-3-phosphatidylserine sodium salt
• L-A-PHOSPHATIDYL-L-SERINE, DIOLEOYL*SODI UM
• l-α-phosphatidyl-l-serine, dioleoyl sodium salt
• 4,6,10-Trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-[[(9Z)-1-oxo-9-octadecenyl]oxy]-, 5-oxide, (2S,19Z)-
• 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE NA SALT

Dioleyl phosphatidylserine

CAS: 6811-55-8

Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.

Formula: C₄₂H₇₈NO₁₀P

Color and Shape: Solid

Molecular weight: 788.04

Ref: TM-T201704